SCHEMBL221511

SCHEMBL221511

Oc1ccc(OC(F)(F)F)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.52
EPHX2 P34913 2/20 0.52
MEN1 O00255 4/20 0.50
KMT2A Q03164 4/20 0.50
ESR1 P03372 1/20 0.50
ESR2 Q92731 1/20 0.50
AURKA O14965 1/20 0.49
TPX2 Q9ULW0 1/20 0.49
KDM4E B2RXH2 2/20 0.47
L3MBTL1 Q9Y468 1/20 0.46
HTT P42858 1/20 0.44
RAB9A P51151 1/20 0.44
FAAH O00519 1/20 0.44
AADAC P22760 1/20 0.44
GPR84 Q9NQS5 1/20 0.44
GPR3 P46089 1/20 0.43
MAOB P27338 1/20 0.43
AOC3 Q16853 1/20 0.43
ALDH1A1 P00352 1/20 0.43
TP53 P04637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4307301 0.93 MEN1 (0.64) MAPTEPHX2MEN1KMT2AESR1
SCHEMBL9589201 0.93 MEN1 (0.64) MAPTEPHX2MEN1KMT2AESR1
SCHEMBL508237 0.93 AURKA (0.57) MAPTEPHX2MEN1KMT2AESR1
SCHEMBL7729335 0.87 GPR84 (0.59) MAPTEPHX2ESR1ESR2KDM4E
SCHEMBL7938064 0.87 NR1H2 (0.56) MAPTEPHX2MEN1KMT2AESR1
SCHEMBL28434916 0.87 MEN1 (0.48) MAPTEPHX2MEN1KMT2AESR1
SCHEMBL15146260 0.87 MAPT (0.56) MAPTEPHX2MEN1KMT2AKDM4E
SCHEMBL7938063 0.87 ESR1 (0.56) MAPTEPHX2ESR1ESR2L3MBTL1
SCHEMBL28434914 0.87 MEN1 (0.48) MAPTEPHX2MEN1KMT2AESR1
SCHEMBL254957 0.86 MAPT (0.56) MAPTEPHX2MEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3144 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12187911-B2 Method for preparing water-soluble acrylic-modified phenolic-modified epoxy resin, water-soluble acrylic-modified phenolic-modified epoxy resin prepared thereby, and aqueous coating composition comprising same SAMHWA PAINTS INDUSTRIES CO., LTD. (KR) 2025-01-07 US claimed
CN-118688342-A Detection method of related substances of delamani starting material 沈阳双鼎制药有限公司 2024-09-24 CN claimed
WO-2024153856-A1 PROCESS FOR THE PREPARATION OF 3-(4,5-DICHLORO-2-(4-(TRIFLUOROMETHOXY)PHENOXY)BENZAMIDO)PYRIDINE 1-OXIDE ORION CORPORATION (FI) 2024-07-25 WO claimed
EP-4392414-A1 INHIBITORS OF NLRP3 PTC Therapeutics, Inc. (US) 2024-07-03 EP claimed
US-20240158396-A1 COMPOUNDS FOR INHIBITING NLRP3 AND USES THEREOF VENTUS THERAPEUTICS U S INC (US) 2024-05-16 US claimed
EP-4363406-A1 NLRP3 INFLAMMASOME INHIBITORS Astrazeneca AB (SE) 2024-05-08 EP claimed
US-20240117213-A1 METHOD FOR PREPARING WATER-SOLUBLE ACRYLIC-MODIFIED PHENOLIC-MODIFIED EPOXY RESIN, WATER-SOLUBLE ACRYLIC-MODIFIED PHENOLIC-MODIFIED EPOXY RESIN PREPARED THEREBY, AND AQUEOUS COATING COMPOSITION COMPRISING SAME SAMHWA PAINTS INDUSTRIES CO., LTD. (KR) 2024-04-11 US claimed
WO-2023028534-A1 INHIBITORS OF NLRP3 PTC THERAPEUTICS, INC. (US) 2023-03-02 WO claimed
WO-2023275366-A1 NLRP3 INFLAMMASOME INHIBITORS ASTRAZENECA AB (SE) 2023-01-05 WO claimed
CN-109988061-B Purification method 罗门哈斯电子材料有限责任公司 2022-08-02 CN claimed
CN-1153779-A 2-(4-pyrazoloxy-pyrimidin-5-yl) acetic acid derivatives SANDOZ LTD (CH) 1997-07-09 CN claimed
CN-1147193-A Insecticidal N-(substd. Arylmethyl)-4-[bis(substd. phenyl) methyl] piperidines FMC CORP (US) 1997-04-09 CN claimed
CN-1139434-A Diazabicyclic neurokinin antagonists PFIZER (US) 1997-01-01 CN claimed
CN-1119015-A Dihalotriazolopyrimidine derivatives as fungicides SHELL INT RESEARCH (NL) 1996-03-20 CN claimed
CN-1075144-A Triazolopyrimidine derivatives SHELL INT RESEARCH (NL) 1993-08-11 CN claimed
EP-0261459-A2 N-benzothiazolyl amides NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1988-03-30 EP claimed
EP-0093976-B1 2,4-DIHALOGENBENZOYL UREAS AND THIOUREAS, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PESTICIDES BAYER AG (DE) 1986-09-10 EP claimed
US-4588844-A Process for preparing aromatic aldehydes BAYER AKTIENGESELLSCHAFT (DE) 1986-05-13 US claimed
EP-0054149-B1 TRIFLUOROMETHOXYPHENYL-(DI)THIOPHOSPHORIC-ACID ESTERS, PROCESS FOR PREPARING THEM AND THEIR USE AS PESTICIDES BASF Aktiengesellschaft (DE) 1984-05-16 EP claimed
EP-0054149-A1 Trifluoromethoxyphenyl-(di)thiophosphoric-acid esters, process for preparing them and their use as pesticides BASF Aktiengesellschaft (DE) 1982-06-23 EP claimed