Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.36 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.36 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.36 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.35 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.35 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.35 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.35 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.35 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.35 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3070467 | 0.78 | EGLN1 (0.57) | EGLN1PRKAG1PRKAA2PRKAB1PRKAA1 | |
| SCHEMBL416845 | 0.72 | FABP6 (0.55) | EGLN1LMNACHEK2PIN1CYP1A2 | |
| SCHEMBL9589711 | 0.68 | EGLN1 (0.56) | EGLN1PRKAG1PRKAA2PRKAB1PRKAA1 | |
| SCHEMBL7152026 | 0.66 | HTR3E (0.57) | CHEK2HRH4HRH3SMN1; SMN2 | |
| SCHEMBL29414225 | 0.66 | KMT2A (0.46) | RHEBCHEK2HRH4HRH3SMN1; SMN2 | |
| SCHEMBL3064168 | 0.66 | KMT2A (0.46) | RHEBCHEK2HRH4HRH3SMN1; SMN2 | |
| SCHEMBL1258540 | 0.66 | EGLN1 (0.57) | EGLN1PRKAG1PRKAA2PRKAB1PRKAA1 | |
| SCHEMBL17137478 | 0.65 | EGLN1 (0.60) | EGLN1PRKAG1PRKAA2PRKAB1PRKAA1 | |
| SCHEMBL17137496 | 0.65 | EGLN1 (0.60) | EGLN1PRKAG1PRKAA2PRKAB1PRKAA1 | |
| SCHEMBL17137479 | 0.65 | EGLN1 (0.60) | EGLN1PRKAG1PRKAA2PRKAB1PRKAA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5216003-A | Antihypoxic, antiischemic agents | G. D. SEARLE & CO. (US) | 1993-06-01 | — | — | US | disclosed |