Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.56 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.38 |
| ▸ | F9 | P00740 | 3/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.37 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.37 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.37 |
| ▸ | RHEB | Q15382 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4954498 | 0.73 | FAAH (0.51) | EGLN1ABL1 | |
| SCHEMBL4309470 | 0.72 | EGLN1 (1.00) | EGLN1HRH4HRH3CACNA1GGRIN2D | |
| SCHEMBL4303435 | 0.69 | EGLN1 (0.65) | EGLN1HRH4HRH3 | |
| SCHEMBL13914872 | 0.68 | HRH4 (0.52) | HRH4HRH3 | |
| SCHEMBL13914871 | 0.68 | HRH4 (0.68) | HRH4HRH3 | |
| SCHEMBL9589724 | 0.68 | EGLN1 (0.41) | EGLN1HRH4HRH3CACNA1GGRIN2D | |
| SCHEMBL1260113 | 0.67 | EGLN1 (0.43) | EGLN1PDE3BPDE3AGRIN2DGRIN3B | |
| SCHEMBL1440395 | 0.66 | GRIN2D (0.47) | PDE3BPDE3ACACNA1GGRIN2DGRIN3B | |
| SCHEMBL12020717 | 0.66 | ALDH1A1 (0.56) | PDE3BPDE3AGRIN2DGRIN3BGRIN1 | |
| SCHEMBL25768258 | 0.66 | HRH4 (0.57) | EGLN1HRH4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5216003-A | Antihypoxic, antiischemic agents | G. D. SEARLE & CO. (US) | 1993-06-01 | — | — | US | disclosed |