Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | NOS3 | P29474 | 2/20 | 0.51 |
| ▸ | NOS1 | P29475 | 2/20 | 0.51 |
| ▸ | NOS2 | P35228 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9589251 | 0.89 | KDM4E (0.52) | KDM4EALDH1A1POLBSIGMAR1TSHR | |
| SCHEMBL9589114 | 0.89 | KDM4E (0.54) | KDM4EALDH1A1NOS3NOS1NOS2 | |
| SCHEMBL9588921 | 0.88 | KDM4E (0.53) | KDM4EALDH1A1NOS3NOS1NOS2 | |
| SCHEMBL9646321 | 0.87 | KDM4E (0.50) | KDM4EALDH1A1 | |
| SCHEMBL9645860 | 0.85 | HTR1A (0.55) | KDM4EALDH1A1 | |
| SCHEMBL9646799 | 0.82 | KDM4E (0.54) | KDM4EALDH1A1TSHR | |
| SCHEMBL9646680 | 0.81 | NPC1 (0.52) | KDM4EALDH1A1POLBCASP1CASP7 | |
| SCHEMBL9646104 | 0.80 | KDM4E (0.52) | KDM4EALDH1A1 | |
| SCHEMBL9592310 | 0.80 | KDM4E (0.53) | KDM4EALDH1A1 | |
| SCHEMBL9647522 | 0.79 | TSHR (0.49) | KDM4EALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5190960-A | Analgesics | ADIR ET COMPAGNIE (FR) | 1993-03-02 | — | — | US | disclosed |