Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 8/20 | 0.55 |
| ▸ | HTR7 | P34969 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9646799 | 0.90 | KDM4E (0.54) | HTR1AHTR7KDM4EALDH1A1LMNA | |
| SCHEMBL9646137 | 0.89 | HTR1A (0.60) | HTR1AHTR7KDM4EALDH1A1 | |
| SCHEMBL9646321 | 0.88 | KDM4E (0.50) | HTR1AKDM4EALDH1A1 | |
| SCHEMBL9646894 | 0.87 | HTR1A (0.70) | HTR1AHTR7 | |
| SCHEMBL9646680 | 0.87 | NPC1 (0.52) | HTR1AKDM4EALDH1A1MAPT | |
| SCHEMBL9647522 | 0.85 | TSHR (0.49) | HTR1AHTR7KDM4EALDH1A1 | |
| SCHEMBL9590519 | 0.85 | KDM4E (0.52) | KDM4EALDH1A1 | |
| SCHEMBL9589114 | 0.84 | KDM4E (0.54) | KDM4EALDH1A1 | |
| SCHEMBL9646450 | 0.84 | KDM4E (0.49) | HTR1AHTR7KDM4EMAPT | |
| SCHEMBL9647603 | 0.84 | ALDH1A1 (0.50) | HTR1AHTR7KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084456-A | Analgesics | SCIENCE ET ORGANISATION (FR) | 1992-01-28 | — | — | US | claimed |
| JP-3077867-A | — | — | None | — | — | JP | disclosed |
| US-5084456-A | Analgesics | SCIENCE ET ORGANISATION (FR) | 1992-01-28 | — | — | US | disclosed |
| JP-H0377867-A | NEW OXAZOLOPYRIDINE DERIVATIVE | SCIENCE & ORGANISATION | 1991-04-03 | — | — | JP | disclosed |