Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.68 |
| ▸ | MEN1 | O00255 | 4/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.67 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9713689 | 0.88 | NPSR1 (1.00) | NPSR1KMT2AMEN1SMN1; SMN2HSD17B10 | |
| SCHEMBL18488506 | 0.83 | NPSR1 (0.73) | NPSR1KMT2AMEN1SMN1; SMN2HSD17B10 | |
| SCHEMBL9591720 | 0.82 | NPSR1 (0.54) | NPSR1KMT2AMEN1SMN1; SMN2HSD17B10 | |
| SCHEMBL9590639 | 0.82 | NPSR1 (0.71) | NPSR1KMT2AMEN1SMN1; SMN2HSD17B10 | |
| SCHEMBL14808444 | 0.81 | KMT2A (1.00) | NPSR1KMT2AMEN1SMN1; SMN2HSD17B10 | |
| Diacetamate SCHEMBL863106 | 0.80 | KMT2A (0.81) | NPSR1KMT2AMEN1SMN1; SMN2HSD17B10 | |
| SCHEMBL27816274 | 0.78 | KMT2A (0.78) | NPSR1KMT2AMEN1SMN1; SMN2HSD17B10 | |
| SCHEMBL18375847 | 0.78 | NPSR1 (0.66) | NPSR1KMT2AMEN1SMN1; SMN2HSD17B10 | |
| SCHEMBL7754914 | 0.78 | NPSR1 (0.71) | NPSR1KMT2AMEN1SMN1; SMN2HSD17B10 | |
| SCHEMBL3681053 | 0.77 | KMT2A (0.75) | NPSR1KMT2AMEN1SMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0469450-A1 | p-Acylaminophenoxycarbamates and Derivatives | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-02-05 | — | — | EP | claimed |
| US-5214061-A | Method of using p-acylaminophenoxycarbamates and derivatives as analgesics | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1993-05-25 | — | — | US | disclosed |
| US-5109011-A | Analgesics | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-04-28 | — | — | US | disclosed |
| EP-0469450-A1 | p-Acylaminophenoxycarbamates and Derivatives | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-02-05 | — | — | EP | disclosed |