Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.70 |
| ▸ | MEN1 | O00255 | 4/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.69 |
| ▸ | RAB9A | P51151 | 1/20 | 0.68 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9592002 | 0.88 | NPSR1 (0.78) | NPSR1KMT2AMEN1SMN1; SMN2HSD17B10 | |
| SCHEMBL18488506 | 0.85 | NPSR1 (0.73) | NPSR1KMT2AMEN1SMN1; SMN2HSD17B10 | |
| SCHEMBL9590639 | 0.83 | NPSR1 (0.71) | NPSR1KMT2AMEN1SMN1; SMN2HSD17B10 | |
| SCHEMBL7754914 | 0.83 | NPSR1 (0.71) | NPSR1KMT2AMEN1SMN1; SMN2HSD17B10 | |
| SCHEMBL14808444 | 0.83 | KMT2A (1.00) | NPSR1KMT2AMEN1SMN1; SMN2HSD17B10 | |
| SCHEMBL6450091 | 0.82 | RAB9A (1.00) | NPSR1KMT2AMEN1RAB9AALDH1A1 | |
| Diacetamate SCHEMBL863106 | 0.81 | KMT2A (0.81) | NPSR1KMT2AMEN1SMN1; SMN2HSD17B10 | |
| SCHEMBL27816274 | 0.79 | KMT2A (0.78) | NPSR1KMT2AMEN1SMN1; SMN2HSD17B10 | |
| SCHEMBL18375847 | 0.79 | NPSR1 (0.66) | NPSR1KMT2AMEN1SMN1; SMN2HSD17B10 | |
| SCHEMBL1404254 | 0.78 | KMT2A (0.75) | NPSR1KMT2AMEN1SMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5157142-A | THIOCARBAMATES AND THEIR DERIVATIVES | HOECHST CELANESE CORPORATION (US) | 1992-10-20 | — | — | US | disclosed |