Panuramine

Panuramine

SCHEMBL2037759

O=C(NC(=O)c1ccccc1)NC1CCN(Cc2ccc3ccccc3c2)CC1

nearest known ligand 0.83

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MCHR1 Q99705 14/20 0.83
DRD4 P21917 3/20 0.77
CCR3 P51677 1/20 0.70
SIGMAR1 Q99720 2/20 0.69
SLC6A12 P48065 1/20 0.65
SLC6A13 Q9NSD5 1/20 0.65
MEN1 O00255 1/20 0.61
KMT2A Q03164 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Panuramine SCHEMBL9749426 0.99 MCHR1 (0.81) MCHR1DRD4CCR3SIGMAR1SLC6A12
SCHEMBL9592451 0.92 DRD4 (0.71) MCHR1DRD4CCR3SIGMAR1SLC6A12
SCHEMBL11057431 0.92 CCR3 (0.84) MCHR1DRD4CCR3
SCHEMBL9592427 0.92 MCHR1 (0.70) MCHR1DRD4CCR3SIGMAR1SLC6A12
SCHEMBL9792346 0.92 MCHR1 (0.84) MCHR1DRD4CCR3SIGMAR1SLC6A12
SCHEMBL9593277 0.90 MCHR1 (0.81) MCHR1DRD4CCR3SIGMAR1SLC6A12
SCHEMBL9594285 0.90 DRD4 (0.75) MCHR1DRD4CCR3
SCHEMBL9592647 0.90 MCHR1 (0.70) MCHR1DRD4CCR3SIGMAR1
SCHEMBL9590523 0.89 DRD4 (0.67) MCHR1DRD4CCR3SIGMAR1SLC6A12
SCHEMBL9601120 0.89 MCHR1 (0.80) MCHR1DRD4CCR3SIGMAR1SLC6A12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 194 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12514883-B2 Compositions and methods for modulating lipid and steroid metabolism THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-01-06 US claimed
WO-2025151884-A1 USE OF GLYCOSAMINOGLYCAN SULFATED POLYSACCHARIDES SUCH AS SODIUM PENTOSAN POLYSULFATE IN COMBINATION WITH PERMEATION AGENTS TO TREAT ALZHEIMER'S DISEASE PARSONS C LOWELL (US) 2025-07-17 WO claimed
EP-4536231-A1 TREATMENT OF ANTIDEPRESSANT RESISTANT SUBJECTS Actinogen Medical Limited (AU) 2025-04-16 EP claimed
CN-119233997-A Tetrahedral antibodies 生物分子控股有限责任公司 2024-12-31 CN claimed
WO-2023235937-A1 TREATMENT OF ANTIDEPRESSANT RESISTANT SUBJECTS Actinogen Medical Limited (AU) 2023-12-14 WO claimed
US-20230381168-A1 ADJUNCTIVE THERAPY FOR DEPRESSION ANEUROTECH BV (BE) 2023-11-30 US claimed
US-11794009-B2 Devices, systems and methods for treating urological and gastrointestinal disorders by electrical stimulation of the foot University of Pittsburgh—of the Commonwealth System of Higher Education (US) 2023-10-24 US claimed
US-20230313301-A1 METHODS OF IDENTIFYING AUTISM SPECTRUM DISORDER WASHINGTON STATE UNIVERSITY 2023-10-05 US claimed
EP-4185712-A2 METHODS OF IDENTIFYING AUTISM SPECTRUM DISORDER Washington State University (US) 2023-05-31 EP claimed
US-20220265641-A1 SEROTONERGIC AGENT AND 5-HT1A-RECEPTOR ANTAGONIST ATLAS PHARMACEUTICALS BV (BE) 2022-08-25 US claimed
US-20170128379-A1 MODIFIED RELEASE PHARMACEUTICAL PREPARATIONS RUBICON RESEARCH PRIVATE LIMITED (IN) 2017-05-11 US claimed
WO-2016106182-A1 DEVICES, SYSTEMS AND METHODS FOR TREATING UROLOGICAL AND GASTROINTESTINAL DISORDERS BY ELECTRICAL STIMULATION OF THE FOOT UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2016-06-30 WO claimed
WO-2016001937-A2 MODIFIED RELEASE PHARMACEUTICAL PREPARATIONS RUBICON RESEARCH PRIVATE LIMITED (IN) 2016-01-07 WO claimed
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
EP-0035374-B1 PIPERIDYL - UREA, - THIOUREA AND - GUANIDINE DERIVATIVES, AND INTERMEDIATES THEREFOR, PROCESSES FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE DERIVATIVES JOHN WYETH & BROTHER LIMITED (GB) 1985-01-30 EP claimed
EP-0035374-A2 Piperidyl - urea, - thiourea and - guanidine derivatives, and intermediates therefor, processes for preparing them and pharmaceutical compositions containing the derivatives JOHN WYETH & BROTHER LIMITED (GB) 1981-09-09 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220265641-A1 SEROTONERGIC AGENT AND 5-HT1A-RECEPTOR ANTAGONIST HTR5A, HTR1A, HTR4 MCHR1 21/4885DRD4 68/4885CCR3 4531/4885
US-20230381168-A1 ADJUNCTIVE THERAPY FOR DEPRESSION HTR2A, HTR3B, HTR5A MCHR1 87/4885DRD4 17/4885CCR3 2711/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.