Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 13/20 | 0.62 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.60 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.55 |
| ▸ | DRD4 | P21917 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9748562 | 0.93 | DRD4 (0.61) | MCHR1ACKR3DRD4 | |
| SCHEMBL9748761 | 0.93 | ACKR3 (0.61) | CCR3MCHR1ACKR3DRD4 | |
| SCHEMBL9589358 | 0.87 | DRD4 (0.67) | CCR3MCHR1ACKR3DRD4 | |
| SCHEMBL9591400 | 0.84 | CCR3 (0.67) | CCR3MCHR1DRD4 | |
| SCHEMBL9592513 | 0.84 | CXCR4 (0.61) | CCR3MCHR1ACKR3DRD4 | |
| SCHEMBL9592175 | 0.84 | CCR3 (0.71) | CCR3MCHR1DRD4 | |
| SCHEMBL9749235 | 0.84 | CCR3 (0.61) | CCR3MCHR1 | |
| SCHEMBL11057431 | 0.84 | CCR3 (0.84) | CCR3MCHR1DRD4 | |
| SCHEMBL9792346 | 0.84 | MCHR1 (0.84) | CCR3MCHR1DRD4 | |
| SCHEMBL9748969 | 0.79 | ACKR3 (0.52) | CCR3MCHR1ACKR3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0234098-B1 | N-[piperidylaminocarbonyl]quinolinecarboxamide derivatives having psychotropic activity | JOHN WYETH & BROTHER LIMITED (GB) | 1992-02-26 | — | — | EP | claimed |
| EP-0234098-B1 | N-[piperidylaminocarbonyl]quinolinecarboxamide derivatives having psychotropic activity | JOHN WYETH & BROTHER LIMITED (GB) | 1992-02-26 | — | — | EP | disclosed |
| US-4778802-A | PSYCHOTROPIC ACTIVITY; ANTIDEPRESSANTS | JOHN WYETH & BROTHER, LTD. (GB) | 1988-10-18 | — | — | US | disclosed |
| EP-0234098-A1 | N-[piperidylaminocarbonyl]quinolinecarboxamide derivatives having psychotropic activity | JOHN WYETH & BROTHER LIMITED (GB) | 1987-09-02 | — | — | EP | disclosed |