Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 1/20 | 0.49 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9593111 | 0.91 | AGTR2 (0.53) | AGTR2 | |
| SCHEMBL9592625 | 0.90 | AGTR2 (0.61) | AGTR2 | |
| SCHEMBL9591408 | 0.89 | AGTR2 (0.50) | AGTR2 | |
| SCHEMBL9592563 | 0.88 | EDNRB (0.49) | AGTR2 | |
| SCHEMBL9594321 | 0.87 | AGTR2 (0.49) | AGTR2 | |
| SCHEMBL9592475 | 0.87 | AGTR2 (0.48) | AGTR2 | |
| SCHEMBL9591907 | 0.85 | PDE4A (0.52) | AGTR2PDE4APDE4BPDE4CPDE4D | |
| Water SCHEMBL9089678 | 0.82 | AGTR1 (0.60) | AGTR2 | |
| Water SCHEMBL9087080 | 0.82 | AGTR2 (0.50) | AGTR2 | |
| SCHEMBL9591325 | 0.82 | AGTR2 (0.53) | AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264439-A | Quinazolinone, triazolinone and pyrimidinone angiotensin II antagonists incorporating a substituted benzyl element | MERCK & CO., INC. (US) | 1993-11-23 | — | — | US | disclosed |