Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 15/20 | 0.74 |
| ▸ | AGTR2 | P50052 | 15/20 | 0.74 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9590776 | 0.91 | AGTR1 (0.75) | AGTR1AGTR2MAPTNPSR1SMN1; SMN2 | |
| SCHEMBL9592779 | 0.90 | AGTR1 (0.75) | AGTR1AGTR2MAPTNPSR1SMN1; SMN2 | |
| SCHEMBL9592385 | 0.88 | AGTR1 (0.76) | AGTR1AGTR2MAPTNPSR1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9589530 | 0.88 | AGTR1 (0.73) | AGTR1AGTR2 | |
| SCHEMBL9654399 | 0.88 | AGTR1 (0.67) | AGTR1AGTR2MAPTNPSR1SMN1; SMN2 | |
| SCHEMBL9590611 | 0.88 | AGTR1 (0.76) | AGTR1AGTR2MAPTNPSR1SMN1; SMN2 | |
| SCHEMBL9653137 | 0.88 | AGTR1 (0.58) | AGTR1AGTR2MAPTNPSR1SMN1; SMN2 | |
| SCHEMBL9592532 | 0.88 | AGTR1 (0.76) | AGTR1AGTR2MAPTNPSR1SMN1; SMN2 | |
| SCHEMBL9592562 | 0.88 | AGTR1 (0.74) | AGTR1AGTR2MAPTNPSR1SMN1; SMN2 | |
| SCHEMBL9653050 | 0.87 | AGTR1 (0.65) | AGTR1AGTR2MAPTNPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5250548-A | Treating hypertension, heart failure | ABBOTT LABORATORIES (US) | 1993-10-05 | — | — | US | disclosed |
| EP-0475206-A2 | Angiotensin II receptor antagonists | ABBOTT LABORATORIES (US) | 1992-03-18 | — | — | EP | disclosed |