Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 14/20 | 0.58 |
| ▸ | AGTR2 | P50052 | 14/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9592999 | 0.88 | AGTR1 (0.74) | AGTR1AGTR2MAPTSMN1; SMN2RAB9A | |
| SCHEMBL9592779 | 0.86 | AGTR1 (0.75) | AGTR1AGTR2MAPTSMN1; SMN2NPSR1 | |
| SCHEMBL9590776 | 0.86 | AGTR1 (0.75) | AGTR1AGTR2MAPTSMN1; SMN2RAB9A | |
| SCHEMBL9592385 | 0.85 | AGTR1 (0.76) | AGTR1AGTR2MAPTSMN1; SMN2NPSR1 | |
| SCHEMBL9655098 | 0.85 | AGTR1 (0.64) | AGTR1AGTR2MAPTSMN1; SMN2NPSR1 | |
| SCHEMBL9590611 | 0.84 | AGTR1 (0.76) | AGTR1AGTR2MAPTSMN1; SMN2NPSR1 | |
| SCHEMBL9655137 | 0.84 | AGTR1 (0.57) | AGTR1AGTR2MAPTSMN1; SMN2RAB9A | |
| SCHEMBL9654340 | 0.84 | AGTR1 (0.57) | AGTR1AGTR2MAPTSMN1; SMN2RAB9A | |
| SCHEMBL9592532 | 0.83 | AGTR1 (0.76) | AGTR1AGTR2MAPTSMN1; SMN2NPSR1 | |
| SCHEMBL9654399 | 0.83 | AGTR1 (0.67) | AGTR1AGTR2MAPTSMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992014468-A1 | PSORIASIS TREATMENT | ABBOTT LABORATORIES (US) | 1992-09-03 | — | — | WO | disclosed |
| US-5104877-A | Psoriasis treatment | ABBOTT LABORATORIES (US) | 1992-04-14 | — | — | US | disclosed |