Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | GPR3 | P46089 | 1/20 | 0.46 |
| ▸ | RARB | P10826 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | RARA | P10276 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10429728 | 0.83 | PPARA (0.53) | HSD11B1PPARALIPGNR1H2NR1H3 | |
| SCHEMBL29434743 | 0.82 | THRA (0.49) | HSD11B1HSD17B10TSHRPPARAGPR3 | |
| SCHEMBL31746979 | 0.82 | RARB (0.50) | HSD11B1HSD17B10TSHRPPARARARB | |
| SCHEMBL9812624 | 0.81 | PPARA (0.54) | HSD11B1PPARALIPGNR1H2NR1H3 | |
| SCHEMBL30784962 | 0.81 | PPARA (0.54) | HSD11B1PPARALIPGNR1H2NR1H3 | |
| SCHEMBL10477129 | 0.80 | KDM4E (0.50) | HSD11B1HSD17B10TSHRPPARAGPR3 | |
| SCHEMBL8521601 | 0.80 | LIPG (0.55) | PPARALIPGNR1H2NR1H3 | |
| SCHEMBL2303757 | 0.80 | LIPG (0.55) | PPARALIPGNR1H2NR1H3 | |
| SCHEMBL761403 | 0.80 | LIPG (0.55) | PPARALIPGNR1H2NR1H3 | |
| SCHEMBL3726514 | 0.80 | LIPG (0.55) | PPARALIPGNR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5227484-A | ANISOTROPIC COMPOUNDS HAVING NEMATIC PHASE AND LIQUID CRYSTAL MIXTURES | MERCK PATENT GMBH (DE) | 1993-07-13 | — | — | US | disclosed |