Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPD | P32754 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | FLT1 | P17948 | 1/20 | 0.37 |
| ▸ | FLT4 | P35916 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9594452 | 0.85 | HPD (0.48) | HPDMEN1PKMKMT2ASMN1; SMN2 | |
| SCHEMBL9191354 | 0.81 | HPD (0.67) | HPDMEN1PKMKMT2ASMN1; SMN2 | |
| SCHEMBL10384013 | 0.80 | HPD (0.44) | HPDMEN1PKMKMT2ASMN1; SMN2 | |
| SCHEMBL10384189 | 0.80 | HPD (0.44) | HPDMEN1PKMKMT2ASMN1; SMN2 | |
| SCHEMBL9595309 | 0.76 | HPD (0.44) | HPDMEN1PKMKMT2ASMN1; SMN2 | |
| SCHEMBL10384019 | 0.75 | HPD (0.41) | HPDMEN1PKMKMT2ASMN1; SMN2 | |
| SCHEMBL10384021 | 0.75 | HPD (0.41) | HPDMEN1PKMKMT2ASMN1; SMN2 | |
| SCHEMBL9239236 | 0.74 | HPD (0.45) | HPDMEN1PKMKMT2ASMN1; SMN2 | |
| SCHEMBL8693826 | 0.73 | SMN1; SMN2 (0.46) | HPDMEN1PKMKMT2ASMN1; SMN2 | |
| SCHEMBL9711516 | 0.71 | HPD (0.48) | HPDMEN1PKMKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5228898-A | SUBSTITUTED BICYCLOHEPTANDIONE DERIVATIVES | NIPPON SODA CO., LTD. (JP) | 1993-07-20 | — | — | US | claimed |