Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPD | P32754 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | FLT1 | P17948 | 1/20 | 0.41 |
| ▸ | FLT4 | P35916 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10384189 | 0.88 | HPD (0.44) | HPDSMN1; SMN2HPGDCYP1A2CYP3A4 | |
| SCHEMBL10384013 | 0.88 | HPD (0.44) | HPDSMN1; SMN2HPGDCYP1A2CYP3A4 | |
| SCHEMBL9594452 | 0.80 | HPD (0.48) | HPDSMN1; SMN2HPGDCYP1A2CYP3A4 | |
| SCHEMBL9191354 | 0.79 | HPD (0.67) | HPDSMN1; SMN2HPGDCYP1A2CYP3A4 | |
| SCHEMBL8985980 | 0.78 | SMN1; SMN2 (0.42) | HPDSMN1; SMN2HPGDCYP1A2CYP3A4 | |
| SCHEMBL8985982 | 0.78 | SMN1; SMN2 (0.42) | HPDSMN1; SMN2HPGDCYP1A2CYP3A4 | |
| SCHEMBL9234637 | 0.78 | SMN1; SMN2 (0.45) | HPDSMN1; SMN2HPGDCYP1A2CYP3A4 | |
| SCHEMBL8693826 | 0.78 | SMN1; SMN2 (0.46) | HPDSMN1; SMN2HPGDCYP1A2CYP3A4 | |
| SCHEMBL9229472 | 0.77 | SMN1; SMN2 (0.44) | HPDSMN1; SMN2HPGDCYP1A2CYP3A4 | |
| SCHEMBL9711617 | 0.77 | HPGD (0.47) | HPDSMN1; SMN2HPGDCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5228898-A | SUBSTITUTED BICYCLOHEPTANDIONE DERIVATIVES | NIPPON SODA CO., LTD. (JP) | 1993-07-20 | — | — | US | disclosed |