Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 13/20 | 0.55 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.54 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.54 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | DRD5 | P21918 | 1/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9593883 | 1.00 | CHRM2 (0.55) | CHRM2CHRM4CHRM1CHRM3CHRM5 | |
| SCHEMBL9593547 | 0.99 | CHRM2 (0.55) | CHRM2CHRM4CHRM1CHRM3CHRM5 | |
| SCHEMBL9593935 | 0.97 | CHRM2 (0.54) | CHRM2CHRM4CHRM1CHRM3CHRM5 | |
| SCHEMBL9267548 | 0.92 | CHRM2 (0.48) | CHRM2CHRM4CHRM1CHRM3CHRM5 | |
| SCHEMBL9594996 | 0.89 | CHRM2 (0.66) | CHRM2CHRM4CHRM1CHRM3CHRM5 | |
| Hydrochloric Acid SCHEMBL9593749 | 0.88 | CHRM2 (0.65) | CHRM2CHRM4CHRM1CHRM3CHRM5 | |
| SCHEMBL9595120 | 0.87 | DRD2 (0.46) | CHRM2CHRM4CHRM1CHRM3DRD2 | |
| SCHEMBL9595138 | 0.87 | DRD2 (0.46) | CHRM2CHRM4CHRM1CHRM3DRD2 | |
| SCHEMBL9274492 | 0.86 | CHRM2 (0.62) | CHRM2CHRM4CHRM1CHRM3CHRM5 | |
| SCHEMBL9594444 | 0.86 | DRD2 (0.45) | CHRM2CHRM4CHRM1CHRM3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264432-A | Antiarrhythmia and anticholinergic agents | ARZNEIMITTELWERK DRESDEN G.M.B.H (DD) | 1993-11-23 | — | — | US | claimed |
| US-5264432-A | Antiarrhythmia and anticholinergic agents | ARZNEIMITTELWERK DRESDEN G.M.B.H (DD) | 1993-11-23 | — | — | US | disclosed |