Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 8/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.40 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.40 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.40 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9595120 | 1.00 | DRD2 (0.46) | DRD2CHRM2RAB9ACHEK1HDAC8 | |
| SCHEMBL9594444 | 0.99 | DRD2 (0.45) | DRD2CHRM2RAB9ACHEK1HDAC8 | |
| SCHEMBL9593989 | 0.88 | CHRM2 (0.52) | CHRM2RAB9AHDAC8CHRM4CHRM1 | |
| SCHEMBL9593883 | 0.87 | CHRM2 (0.55) | DRD2CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL9594641 | 0.87 | CHRM2 (0.55) | DRD2CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL9593547 | 0.86 | CHRM2 (0.55) | DRD2CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL9827608 | 0.85 | RAB9A (0.48) | DRD2CHRM2RAB9ACHEK1CHRM4 | |
| SCHEMBL9593935 | 0.85 | CHRM2 (0.54) | DRD2CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL9595164 | 0.85 | CHRM2 (0.54) | DRD2CHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL9596500 | 0.84 | CHRM2 (0.54) | DRD2CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264432-A | Antiarrhythmia and anticholinergic agents | ARZNEIMITTELWERK DRESDEN G.M.B.H (DD) | 1993-11-23 | — | — | US | disclosed |