Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27289936 | 0.88 | ALDH1A1 (0.42) | ALDH1A1CHRNB2CHRNA4MAPTCYP3A4 | |
| SCHEMBL27480691 | 0.86 | ALDH1A1 (0.39) | ALDH1A1CHRNB2CHRNA4MAPTCYP3A4 | |
| SCHEMBL1747693 | 0.84 | ALDH1A1 (0.41) | ALDH1A1CHRNB2CHRNA4MAPTCYP3A4 | |
| SCHEMBL27480692 | 0.84 | LMNA (0.32) | ALDH1A1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL1747691 | 0.84 | ALDH1A1 (0.41) | ALDH1A1CHRNB2CHRNA4MAPTCYP3A4 | |
| SCHEMBL1747879 | 0.82 | ALDH1A1 (0.40) | ALDH1A1CHRNB2CHRNA4MAPTCYP3A4 | |
| SCHEMBL1747880 | 0.82 | ALDH1A1 (0.40) | ALDH1A1CHRNB2CHRNA4MAPTCYP3A4 | |
| SCHEMBL7663625 | 0.82 | ALDH1A1 (0.45) | ALDH1A1CHRNB2CHRNA4MAPTCYP3A4 | |
| SCHEMBL8064562 | 0.80 | MAPT (0.36) | MAPT | |
| SCHEMBL27294629 | 0.79 | ALDH1A1 (0.41) | ALDH1A1CHRNB2CHRNA4MAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1083432-C | Alpha-unsaturated amines, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2002-04-24 | — | — | CN | disclosed |
| CN-1036649-C | Alpha-unsaturated amines, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1997-12-10 | — | — | CN | disclosed |
| CN-1027447-C | Insecticidal/acaricidal composition containing alpha-unsaturated amine | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-01-18 | — | — | CN | disclosed |
| CN-1093083-A | The method for preparing α-unsaturated amine or its salt | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1994-10-05 | — | — | CN | disclosed |
| CN-1091737-A | The method for preparing amine compound or its salt | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1994-09-07 | — | — | CN | disclosed |
| US-5225423-A | BUTENONE COMPOUNDS, THEIR PREPARATION AND THEIR USE AS PESTICIDES | SHELL RESEARCH LIMITED (GB) | 1993-07-06 | — | — | US | disclosed |
| CN-1063014-A | Stable composition pesticide | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1992-07-29 | — | — | CN | disclosed |
| CN-1031079-A | Alpha-unsaturated amines, process for their production and their use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1989-02-15 | — | — | CN | disclosed |