Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 3/20 | 0.37 |
| ▸ | FNTB | P49356 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CMA1 | P23946 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 6/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9587779 | 0.94 | FNTA (0.37) | FNTAFNTBNPC1CMA1MAPT | |
| SCHEMBL9587617 | 0.93 | FNTA (0.36) | FNTAFNTBNPC1CMA1MAPT | |
| SCHEMBL9587003 | 0.93 | FNTA (0.40) | FNTAFNTBNPC1CMA1MAPT | |
| SCHEMBL9587080 | 0.92 | TP53 (0.35) | FNTAFNTBCMA1ALDH1A1LMNA | |
| SCHEMBL9586921 | 0.87 | FNTA (0.37) | FNTAFNTBCMA1MAPTALDH1A1 | |
| SCHEMBL9587686 | 0.85 | FNTA (0.39) | FNTAFNTBNPC1MAPTALDH1A1 | |
| SCHEMBL9586521 | 0.85 | FNTA (0.39) | FNTAFNTBNPC1CMA1MAPT | |
| SCHEMBL9605281 | 0.85 | MMP1 (0.34) | ALDH1A1MAPK1 | |
| SCHEMBL7480667 | 0.81 | L3MBTL1 (0.47) | MAPTALDH1A1LMNACRHBPCRHR2 | |
| SCHEMBL9586936 | 0.80 | FNTA (0.39) | FNTAFNTBMAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993018030-A1 | BENZIMIDAZOLE DERIVATIVES AS ANGIOTENSIN II ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-09-16 | — | — | WO | disclosed |