Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | HPD | P32754 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | FLT4 | P35916 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8985982 | 0.79 | SMN1; SMN2 (0.42) | SMN1; SMN2CYP2C19HPDHPGDCYP1A2 | |
| SCHEMBL8985980 | 0.79 | SMN1; SMN2 (0.42) | SMN1; SMN2CYP2C19HPDHPGDCYP1A2 | |
| SCHEMBL8713774 | 0.77 | SMN1; SMN2 (0.46) | SMN1; SMN2CYP2C19HPDHPGDCYP1A2 | |
| SCHEMBL9711611 | 0.77 | HPD (0.49) | SMN1; SMN2CYP2C19HPDHPGDCYP1A2 | |
| SCHEMBL9595309 | 0.77 | HPD (0.44) | SMN1; SMN2CYP2C19HPDHPGDCYP1A2 | |
| SCHEMBL9234637 | 0.76 | SMN1; SMN2 (0.45) | SMN1; SMN2CYP2C19HPDHPGDCYP1A2 | |
| SCHEMBL8693826 | 0.76 | SMN1; SMN2 (0.46) | SMN1; SMN2CYP2C19HPDHPGDCYP1A2 | |
| SCHEMBL9711575 | 0.76 | NPC1 (0.43) | SMN1; SMN2CYP2C19HPDHPGDCYP1A2 | |
| SCHEMBL9711511 | 0.75 | SMN1; SMN2 (0.43) | SMN1; SMN2CYP2C19HPDHPGDCYP1A2 | |
| SCHEMBL9191354 | 0.74 | HPD (0.67) | SMN1; SMN2CYP2C19HPDHPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641780-A1 | HETEROCYCLIC CYCLOHEXANEDIONE DERIVATIVE, PRODUCTION THEREOF, AND HERBICIDE | NIPPON SODA CO., LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |