SCHEMBL95956

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL97475	0.88	NR1H2 (0.43)	TSHRTP53CNR2ESR1NPSR1
	SCHEMBL411733	0.86	TSHR (0.52)	TSHRTP53CNR2TAAR1ESR1
	SCHEMBL96482	0.86	NPC1 (0.45)	TSHRCNR2KCNH2
	SCHEMBL7285412	0.85	TSHR (0.44)	TSHRTP53CNR2TAAR1ESR1
	SCHEMBL96181	0.84	NPC1 (0.47)	TSHRTP53CNR2MEN1KMT2A
	Hydrochloric Acid SCHEMBL2142184	0.84	TSHR (0.50)	TSHRTP53CNR2TAAR1ESR1
	Water SCHEMBL31498994	0.84	TSHR (0.50)	TSHRTP53CNR2TAAR1ESR1
	SCHEMBL15161710	0.82	TSHR (0.39)	TSHRTP53CNR2TAAR1NPSR1
	SCHEMBL95544	0.82	TSHR (0.59)	TSHRCNR2TAAR1L3MBTL1ALDH1A1
	Nitrogen SCHEMBL4599415	0.82	TSHR (0.48)	TSHRTP53CNR2TAAR1ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.