Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.59 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diethylaniline SCHEMBL9000098 | 0.85 | TSHR (0.70) | TSHRCNR2TAAR1MEN1KMT2A | |
| Diethylaniline SCHEMBL17594 | 0.85 | TSHR (0.70) | TSHRCNR2TAAR1MEN1KMT2A | |
| SCHEMBL9145309 | 0.85 | TSHR (0.44) | TSHRCNR2TAAR1MEN1KMT2A | |
| Diethylaniline SCHEMBL28201804 | 0.83 | TSHR (0.61) | TSHRCNR2TAAR1MEN1KMT2A | |
| Diethylaniline SCHEMBL9638069 | 0.82 | TSHR (0.67) | TSHRCNR2TAAR1MEN1KMT2A | |
| Diethylaniline SCHEMBL30880867 | 0.82 | TSHR (0.67) | TSHRCNR2TAAR1MEN1KMT2A | |
| Diethylaniline SCHEMBL1920410 | 0.82 | TSHR (0.67) | TSHRCNR2TAAR1MEN1KMT2A | |
| Diethylaniline SCHEMBL2215318 | 0.82 | TSHR (0.67) | TSHRCNR2TAAR1MEN1KMT2A | |
| Diethylaniline SCHEMBL31229134 | 0.82 | TSHR (0.67) | TSHRCNR2TAAR1MEN1KMT2A | |
| Diethylaniline SCHEMBL184484 | 0.82 | TSHR (0.67) | TSHRCNR2TAAR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 221 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100048893-A1 | Substituted arylalkanoic acid derivatives and use thereof | ASAHI KASEI PHARMA CORPORATION (JP) | 2010-02-25 | — | — | US | claimed |
| EP-2006271-A9 | SUBSTITUTED BICYCLIC CYCLIC DERIVATIVE AND USE THEREOF | Asahi Kasei Pharma Corporation (JP) | 2009-07-29 | — | — | EP | claimed |
| CN-101410366-A | Substituted bicyclic ring derivatives and uses thereof | ASAHI KASEI PHARMA CORP (JP) | 2009-04-15 | — | — | CN | claimed |
| US-20090062530-A1 | Substituted arylalkanoic acid derivatives and use thereof | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-03-05 | — | — | US | claimed |
| US-20090054401-A1 | Substituted bicyclic derivatives and use thereof | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-02-26 | — | — | US | claimed |
| EP-2006271-A2 | SUBSTITUTED BICYCLIC CYCLIC DERIVATIVE AND USE THEREOF | Asahi Kasei Pharma Corporation (JP) | 2008-12-24 | — | — | EP | claimed |
| US-7034129-B2 | Process for surface functionalsation of polymeric substrates using diaryl carbenes as reactive intermediates | ISIS INNOVATION LIMITED (GB) | 2006-04-25 | — | — | US | claimed |
| EP-1124791-B1 | SURFACE FUNCTIONALISATION | ISIS INNOVATION (GB) | 2005-01-12 | — | — | EP | claimed |
| US-20040127691-A1 | Process for surface functionalsation of polymeric substrates using diaryl carbenes as reactive intermediates | MOLONEY MARK GERARD (GB) | 2004-07-01 | — | — | US | claimed |
| US-6699527-B1 | FOR DYEING, OF SUBSTRATES SUCH AS COTTON, A VARIETY OF PLASTICS, POLYSTYRENE, NYLON, CONTROLLED PORE GLASS, SILICA, AN ETHYLENE POLYMER OR POLYTETRAFLUOROETHYLENE | ISIS INNOVATION LIMITED (GB) | 2004-03-02 | — | — | US | claimed |
| EP-1129083-A1 | ISOTHIAZOLECARBOXYLIC ACID DERIVATIVES | NIHON BAYER AGROCHEM K.K. (JP) | 2001-09-05 | — | — | EP | claimed |
| EP-1124791-A1 | SURFACE FUNCTIONALISATION | ISIS INNOVATION LIMITED (GB) | 2001-08-22 | — | — | EP | claimed |
| WO-2000029398-A1 | ISOTHIAZOLECARBOXYLIC ACID DERIVATIVES | NIHON BAYER AGROCHEM K.K. (JP) | 2000-05-25 | — | — | WO | claimed |
| WO-2000026180-A1 | SURFACE FUNCTIONALISATION | ISIS INNOVATION LIMITED (GB) | 2000-05-11 | — | — | WO | claimed |
| JP-8151420-A | — | — | None | — | — | JP | disclosed |
| EP-3835329-B1 | POLYMERIZATION INITIATOR, CURABLE COMPOSITION, DENTAL MATERIAL, AND PREPARATION KIT FOR CURABLE COMPOSITION | MITSUI CHEMICALS INC (JP) | 2024-05-01 | — | — | EP | disclosed |
| CN-108375878-B | Polymerizable composition, method for producing cured film, and cured film | 东京应化工业株式会社 | 2023-12-08 | — | — | CN | disclosed |
| US-4683234-A | HYPOTENSIVE AGENTS, ANTI-ANGINA | SUNTORY LIMITED (JP) | 1987-07-28 | — | — | US | disclosed |
| EP-0162208-A2 | Novel N-substituted 3,4-dihydropyrimidine derivatives, processes for preparing them and pharmaceutical compositions | SUNTORY KABUSHIKI KAISHA, also known as SUNTORY LTD. (JP) | 1985-11-27 | — | — | EP | disclosed |
| EP-0106023-A2 | End-capped polyarylene polyethers, articles made therefrom and process for preparing such polyarylene polyethers | AMOCO CORPORATION (US) | 1984-04-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054401-A1 | Substituted bicyclic derivatives and use thereof | LTB4R2, LTC4S, LTB4R | TSHR 1642/4885CNR2 31/4885TAAR1 1127/4885 |
| US-20100048893-A1 | Substituted arylalkanoic acid derivatives and use thereof | CYSLTR1, CYSLTR2, LTB4R2 | TSHR 536/4885CNR2 67/4885TAAR1 541/4885 |
| US-20040127691-A1 | Process for surface functionalsation of polymeric substrates using diaryl carbenes as reactive intermediates | CYCS, CTTN, CYBB | TSHR 3888/4885CNR2 164/4885TAAR1 860/4885 |
| US-20090062530-A1 | Substituted arylalkanoic acid derivatives and use thereof | CYSLTR1, CYSLTR2, LTB4R2 | TSHR 536/4885CNR2 67/4885TAAR1 541/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.