Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | SCN1A | P35498 | 3/20 | 0.44 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.44 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | HRH2 | P25021 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9594241 | 0.80 | HTT (0.44) | LMNACYP2D6HTTSCN1ASCN2A | |
| SCHEMBL9594297 | 0.77 | SCN1A (0.47) | LMNACYP2D6HTTSCN1ASCN2A | |
| SCHEMBL6276844 | 0.73 | MAPT (0.42) | LMNACYP2D6HTTSCN1ASCN2A | |
| Dimethylamine SCHEMBL29198789 | 0.72 | HTT (0.55) | LMNACYP2D6HTTSCN1ASCN2A | |
| SCHEMBL11813722 | 0.72 | SCN1A (0.46) | LMNACYP2D6HTTSCN1ASCN2A | |
| SCHEMBL13359839 | 0.71 | CYP2D6 (0.50) | LMNACYP2D6DRD3SMN1; SMN2 | |
| SCHEMBL3333230 | 0.69 | SIGMAR1 (0.68) | LMNACYP2D6HTTSCN1ASCN2A | |
| SCHEMBL3992907 | 0.69 | SCN1A (0.55) | LMNACYP2D6HTTSCN1ASCN2A | |
| SCHEMBL4667564 | 0.68 | SCN1A (0.65) | LMNACYP2D6HTTSCN1ASCN2A | |
| Hydrochloric Acid SCHEMBL28100967 | 0.68 | HTT (0.69) | LMNACYP2D6HTTSCN1ASCN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5192765-A | Smooth muscle, bowel, bladder and airway diseases | PFIZER INC. (US) | 1993-03-09 | — | — | US | disclosed |
| EP-0365093-B1 | MUSCARINIC RECEPTOR ANTAGONISTS | PFIZER INC. (US) | 1992-09-02 | — | — | EP | disclosed |
| EP-0438533-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | Pfizer Limited (GB) | 1991-07-31 | — | — | EP | disclosed |
| WO-1990004583-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | PFIZER LIMITED (GB) | 1990-05-03 | — | — | WO | disclosed |
| EP-0365093-A1 | Muscarinic receptor antagonists | PFIZER INC. (US) | 1990-04-25 | — | — | EP | disclosed |