Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.68 |
| ▸ | HTT | P42858 | 2/20 | 0.66 |
| ▸ | SCN1A | P35498 | 3/20 | 0.56 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.56 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.56 |
| ▸ | HTR2A | P28223 | 3/20 | 0.56 |
| ▸ | HRH1 | P35367 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.56 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.56 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.56 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28100967 | 0.98 | HTT (0.69) | SIGMAR1HTTSCN1ASCN2ASCN3A | |
| Hydrochloric Acid SCHEMBL11382229 | 0.87 | SIGMAR1 (0.62) | SIGMAR1HTTSCN1ASCN2ASCN3A | |
| Tofenacin SCHEMBL49290 | 0.85 | CYP2D6 (0.64) | SIGMAR1HTTSCN1ASCN2ASCN3A | |
| Tofenacin SCHEMBL637494 | 0.84 | LMNA (0.65) | SIGMAR1HTTHTR2AHRH1LMNA | |
| SCHEMBL9051194 | 0.81 | SIGMAR1 (1.00) | SIGMAR1HTTSCN1ASCN2ASCN3A | |
| SCHEMBL5183470 | 0.81 | SIGMAR1 (0.49) | SIGMAR1HTTSCN1ASCN2ASCN3A | |
| SCHEMBL4905532 | 0.81 | SIGMAR1 (0.49) | SIGMAR1HTTSCN1ASCN2ASCN3A | |
| SCHEMBL5184742 | 0.81 | SIGMAR1 (0.49) | SIGMAR1HTTSCN1ASCN2ASCN3A | |
| SCHEMBL4667564 | 0.80 | SCN1A (0.65) | SIGMAR1HTTSCN1ASCN2ASCN3A | |
| Hydrochloric Acid SCHEMBL5186556 | 0.80 | HTT (0.49) | SIGMAR1HTTSCN1ASCN2ASCN3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113151188-A | Hybridoma cell strain capable of secreting diphenhydramine monoclonal antibody and application thereof | 江南大学 | 2021-07-23 | — | — | CN | claimed |
| CN-108387652-B | Method for detecting impurities in compound paracetamol diphenhydramine tablets | 四川省食品药品检验检测院 | 2021-03-02 | — | — | CN | claimed |
| CN-113151188-B | Hybridoma cell strain capable of secreting diphenhydramine monoclonal antibody and application thereof | 江南大学 | 2022-10-18 | — | — | CN | disclosed |
| CN-113151188-A | Hybridoma cell strain capable of secreting diphenhydramine monoclonal antibody and application thereof | 江南大学 | 2021-07-23 | — | — | CN | disclosed |
| CN-108387652-B | Method for detecting impurities in compound paracetamol diphenhydramine tablets | 四川省食品药品检验检测院 | 2021-03-02 | — | — | CN | disclosed |
| WO-2016037189-A1 | SEMI-SOLID CHEWABLE DOSAGE FORM FOR OVER-THE-COUNTER MEDICATIONS AND METHODS FOR PRODUCING SAME | SANTA CRUZ PHARMACEUTICALS, INC. (US) | 2016-03-10 | — | — | WO | disclosed |
| US-20150174264-A1 | Oligomer-Antihistamine Conjugates | NEKTAR THERAPEUTICS (US) | 2015-06-25 | — | — | US | disclosed |
| US-20150174264-A1 | Oligomer-Antihistamine Conjugates | NEKTAR THERAPEUTICS (US) | 2015-06-25 | — | — | US | disclosed |
| US-20150174264-A1 | Oligomer-Antihistamine Conjugates | NEKTAR THERAPEUTICS (US) | 2015-06-25 | — | — | US | disclosed |
| EP-2121031-B1 | OLIGOMER-ANTIHISTAMINE CONJUGATES | NEKTAR THERAPEUTICS (US) | 2013-10-16 | — | — | EP | disclosed |
| EP-2121031-B1 | OLIGOMER-ANTIHISTAMINE CONJUGATES | NEKTAR THERAPEUTICS (US) | 2013-10-16 | — | — | EP | disclosed |
| US-20070232622-A1 | Small molecule toll-like receptor (TLR) antagonists | COLEY PHARMACEUTICAL GMBH (DE) | 2007-10-04 | — | — | US | disclosed |
| US-20070232622-A1 | Small molecule toll-like receptor (TLR) antagonists | COLEY PHARMACEUTICAL GMBH (DE) | 2007-10-04 | — | — | US | disclosed |
| US-7078406-B2 | Substituted diphenyloxazoles, the synthesis thereof, and the use thereof as fluorescence probes | JOHNSON & JOHNSON PHARMACEUTICAL RESEARCH & DEVELOPMENT, L.L.C. (US) | 2006-07-18 | — | — | US | disclosed |
| US-20040248851-A1 | Substituted diphenyloxazoles, the synthesis thereof, and the use thereof as fluorescence probes | Life Technologies Corporation | 2004-12-09 | — | — | US | disclosed |
| US-6815445-B2 | FOR USE AS FLUORESCENCE DYES AND PROBES | Life Technologies Corporation | 2004-11-09 | — | — | US | disclosed |
| EP-1442027-A1 | SUBSTITUTED DIPHENYLOXAZOLES, THE SYNTHESIS THEREOF, AND THE USE THEREOF AS FLUORESCENCE PROBES | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2004-08-04 | — | — | EP | disclosed |
| US-20030105111-A1 | Substituted diphenyloxazoles, the synthesis thereof, and the use thereof as fluorescence probes | 3-DIMENSIONAL PHARMACEUTICALS, INC. | 2003-06-05 | — | — | US | disclosed |
| WO-2003031419-A1 | SUBSTITUTED DIPHENYLOXAZOLES, THE SYNTHESIS THEREOF, AND THE USE THEREOF AS FLUORESCENCE PROBES | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2003-04-17 | — | — | WO | disclosed |
| US-4097528-A | N-(2-diphenylmethoxyethyl)-N-(1-methyl-2-phenoxyethyl)-N-methyl! amine | DOCTOR ANDREU, S.A. (ES) | 1978-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070232622-A1 | Small molecule toll-like receptor (TLR) antagonists | TLR3, TLR8, TLR7 | SIGMAR1 342/4885HTT 4396/4885SCN1A 3037/4885 |
| US-20150174264-A1 | Oligomer-Antihistamine Conjugates | HRH4, HRH1, HRH3 | SIGMAR1 860/4885HTT 12/4885SCN1A 3216/4885 |
| US-20040248851-A1 | Substituted diphenyloxazoles, the synthesis thereof, and the use thereof as fluorescence probes | DHFR, FPR1, CYP1A1 | SIGMAR1 1287/4885HTT 3925/4885SCN1A 3939/4885 |
| US-20030105111-A1 | Substituted diphenyloxazoles, the synthesis thereof, and the use thereof as fluorescence probes | DHFR, FPR1, CYP1A1 | SIGMAR1 1287/4885HTT 3925/4885SCN1A 3939/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.