SCHEMBL9595751

SCHEMBL9595751

O=C1OCN(C(=O)O)[C@H]1CC1CCCCC1

nearest known ligand 0.34

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 4/20 0.34
MMP9 P14780 3/20 0.34
MMP7 P09237 2/20 0.34
MMP3 P08254 1/20 0.34
NAAA Q02083 1/20 0.33
USP2 O75604 1/20 0.32
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30
LTB4R Q15722 1/20 0.30
LTB4R2 Q9NPC1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22122351 0.95 USP2 (0.32) USP2
SCHEMBL22122354 0.95 USP2 (0.32) USP2
SCHEMBL22552473 0.92 USP2 (0.33) USP2
SCHEMBL22552472 0.92 USP2 (0.33) USP2
SCHEMBL4397835 0.75 USP2 (0.40) USP2
SCHEMBL31162268 0.73 USP2 (0.34) USP2
SCHEMBL4397832 0.72 USP2 (0.38) USP2
SCHEMBL8040101 0.70 USP2 (0.32) USP2
SCHEMBL27222026 0.68 USP2 (0.31) USP2
SCHEMBL21837883 0.67 USP2 (0.33) USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1993001174-A1 THIAZOLIDINE DERIVATIVES AND THEIR USE AS ANTI-VIRAL COMPOUNDS GLAXO GROUP LIMITED (GB) 1993-01-21 WO disclosed