SCHEMBL22552472

SCHEMBL22552472

O=C1OCN(C(=O)O)[C@H]1CC1CC1

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22552473 1.00 USP2 (0.33) USP2
SCHEMBL22122351 0.93 USP2 (0.32) USP2
SCHEMBL22122354 0.93 USP2 (0.32) USP2
SCHEMBL9595751 0.92 MMP1 (0.34) USP2
SCHEMBL4397835 0.79 USP2 (0.40) USP2
SCHEMBL4397844 0.79 USP2 (0.40) USP2
SCHEMBL31162268 0.77 USP2 (0.34) USP2
SCHEMBL4397832 0.76 USP2 (0.38) USP2
SCHEMBL4405682 0.76 USP2 (0.38) USP2
SCHEMBL4397828 0.76 USP2 (0.38) USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11279735-B2 Cyclic peptide antibiotics GENENTECH, INC. (US) 2022-03-22 US disclosed
US-20200331968-A1 CYCLIC PEPTIDE ANTIBIOTICS GENENTECH, INC. (US) 2020-10-22 US disclosed
CN-111148739-A Cyclopeptide antibiotics 豪夫迈·罗氏有限公司 2020-05-12 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200331968-A1 CYCLIC PEPTIDE ANTIBIOTICS NPPA, LNPEP, CLPP USP2 1163/4885
US-11279735-B2 Cyclic peptide antibiotics NPPA, LNPEP, CLPP USP2 1163/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.