Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.54 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.53 |
| ▸ | MGLL | Q99685 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ACACB | O00763 | 1/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | CCR3 | P51677 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10607268 | 0.90 | EPHX2 (0.59) | EPHX2SLC6A2SLC6A4SLC6A3ABHD6 | |
| SCHEMBL10606827 | 0.87 | EPHX2 (0.64) | EPHX2SLC6A2SLC6A4SLC6A3ABHD6 | |
| SCHEMBL2636372 | 0.87 | ABHD6 (0.51) | EPHX2SLC6A2SLC6A4SLC6A3ABHD6 | |
| Dezinamide SCHEMBL635558 | 0.86 | SLC6A2 (0.54) | EPHX2SLC6A2SLC6A4SLC6A3ABHD6 | |
| SCHEMBL2636375 | 0.83 | ABHD6 (0.50) | EPHX2SLC6A2SLC6A4SLC6A3ABHD6 | |
| Fluzinamide SCHEMBL636118 | 0.83 | EPHX2 (0.52) | EPHX2SLC6A2SLC6A4SLC6A3ABHD6 | |
| SCHEMBL9596614 | 0.83 | ABHD6 (0.50) | EPHX2SLC6A2SLC6A4SLC6A3ABHD6 | |
| Fluzinamide SCHEMBL30306317 | 0.83 | EPHX2 (0.52) | EPHX2SLC6A2SLC6A4SLC6A3ABHD6 | |
| SCHEMBL9596930 | 0.83 | ABHD6 (0.50) | EPHX2SLC6A2SLC6A4SLC6A3ABHD6 | |
| SCHEMBL9596860 | 0.83 | ABHD6 (0.50) | EPHX2SLC6A2SLC6A4SLC6A3ABHD6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5183902-A | Muscle relaxants | A. H. ROBINS COMPANY, INCORPORATED (US) | 1993-02-02 | — | — | US | disclosed |
| US-5151418-A | Muscle relaxants | A. H. ROBINS COMPANY, INCORPORATED (US) | 1992-09-29 | — | — | US | disclosed |
| US-5068231-A | Ureas and thioureas for relaxing muscles | A. H. ROBINS COMPANY INCORPORATED (US) | 1991-11-26 | — | — | US | disclosed |
| US-4956359-A | CARBOXAMIDES OR THIOCARBOXAMIDES OF ARYL OXY OR THIO AZETIDINES | A. H. ROBINS COMPANY, INC. (US) | 1990-09-11 | — | — | US | disclosed |