Dezinamide

Dezinamide

SCHEMBL635558

NC(=O)N1CC(Oc2cccc(C(F)(F)F)c2)C1

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.54
SLC6A4 P31645 1/20 0.54
SLC6A3 Q01959 1/20 0.54
ABHD6 Q9BV23 2/20 0.53
MGLL Q99685 1/20 0.53
EPHX2 P34913 1/20 0.49
TP53 P04637 1/20 0.47
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
ACACB O00763 1/20 0.45
KDM4E B2RXH2 2/20 0.45
BTK Q06187 1/20 0.45
SCN9A Q15858 1/20 0.44
CHRM2 P08172 1/20 0.44
CHRM4 P08173 1/20 0.44
CHRM5 P08912 1/20 0.44
CHRM1 P11229 1/20 0.44
CHRM3 P20309 1/20 0.44
PRSS1 P07477 1/20 0.43
ACR P10323 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2636372 0.90 ABHD6 (0.51) SLC6A2SLC6A4SLC6A3ABHD6MGLL
SCHEMBL9595992 0.86 EPHX2 (0.54) SLC6A2SLC6A4SLC6A3ABHD6MGLL
SCHEMBL2636375 0.86 ABHD6 (0.50) SLC6A2SLC6A4SLC6A3ABHD6MGLL
Fluzinamide SCHEMBL30306317 0.83 EPHX2 (0.52) SLC6A2SLC6A4SLC6A3ABHD6MGLL
Fluzinamide SCHEMBL636118 0.83 EPHX2 (0.52) SLC6A2SLC6A4SLC6A3ABHD6MGLL
SCHEMBL9596614 0.83 ABHD6 (0.50) SLC6A2SLC6A4SLC6A3ABHD6MGLL
SCHEMBL9596930 0.83 ABHD6 (0.50) SLC6A2SLC6A4SLC6A3ABHD6MGLL
SCHEMBL9596860 0.83 ABHD6 (0.50) SLC6A2SLC6A4SLC6A3ABHD6MGLL
SCHEMBL9354901 0.83 LIPG (0.49) EPHX2ACACBLIPGGAA
SCHEMBL2636858 0.83 EPHX2 (0.54) SLC6A2SLC6A4SLC6A3ABHD6MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 277 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
US-8268352-B2 Modified release composition for highly soluble drugs TORRENT PHARMACEUTICALS LIMITED (IN) 2012-09-18 US claimed
US-8263125-B2 Dosage form for high dose-high solubility active ingredients that provides for immediate release and modified release of the active ingredients TORRENT PHARMACEUTICALS LIMITED (IN) 2012-09-11 US claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US claimed
CN-101330905-A Freeze-drying process and products obtained thereby SCIDOSE LLC (US) 2008-12-24 CN claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
US-20060024365-A1 Novel dosage form VAYA NAVIN 2006-02-02 US claimed
US-20060018934-A1 Novel drug delivery system TORRENT PHARMACEUTICALS LIMITED (IN) 2006-01-26 US claimed
WO-2000066096-A2 USE OF ANTIEPILEPTICS FOR TREATING RESPIRATORY DISORDERS, IN PARTICULAR ASTHMATIC DISORDERS LOMIA MERAB (GE) 2000-11-09 WO claimed
US-5151418-A Muscle relaxants A. H. ROBINS COMPANY, INCORPORATED (US) 1992-09-29 US claimed
US-5068231-A Ureas and thioureas for relaxing muscles A. H. ROBINS COMPANY INCORPORATED (US) 1991-11-26 US claimed
EP-0194112-B1 3-ARYL-OXYAZETIDINECARBOXAMIDES HAVING ANTI-MUSCLE TENSION, ANTI-MUSCLE SPASTICITY, ANTICONVULSANT AND ANTIEPILECTIC ACTIVITY A.H. ROBINS COMPANY, INCORPORATED (US) 1990-05-23 EP claimed
EP-0102740-B1 N-FORMYL AND N-HYDROXYMETHYL-3-PHENOXY-1-AZETIDINECARBOXAMIDES AND THEIR PREPARATION AND USE A.H. ROBINS COMPANY, INCORPORATED (US) 1986-11-05 EP claimed
EP-0102194-B1 3-PHENOXY-1-AZETIDINECARBOXAMIDES AND THEIR USE AND PREPARATION A.H. ROBINS COMPANY, INCORPORATED (US) 1986-10-22 EP claimed
EP-0194112-A1 3-Aryl-oxyazetidinecarboxamides having anti-muscle tension, anti-muscle spasticity, anticonvulsant and antiepilectic activity A.H. ROBINS COMPANY, INCORPORATED (US) 1986-09-10 EP claimed
US-4571393-A ANTICONVULSANT TREATMENT FOR MAMMALS A. H. ROBINS COMPANY, INCORPORATED (US) 1986-02-18 US claimed
EP-0102740-A1 N-formyl and n-hydroxymethyl-3-phenoxy-1-azetidinecarboxamides and their preparation and use A.H. ROBINS COMPANY, INCORPORATED (US) 1984-03-14 EP claimed
EP-0102194-A1 3-Phenoxy-1-azetidinecarboxamides and their use and preparation A.H. ROBINS COMPANY, INCORPORATED (US) 1984-03-07 EP claimed