⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29881812 | 1.00 | — | — | |
| Ether SCHEMBL2885132 | 0.85 | TSHR (0.35) | — | |
| SCHEMBL14892395 | 0.80 | TSHR (0.39) | — | |
| SCHEMBL1022119 | 0.79 | TRPA1 (0.42) | — | |
| SCHEMBL29456798 | 0.79 | TRPA1 (0.42) | — | |
| SCHEMBL464794 | 0.77 | TSHR (0.53) | — | |
| SCHEMBL170136 | 0.72 | — | — | |
| SCHEMBL31463495 | 0.72 | — | — | |
| SCHEMBL1314056 | 0.72 | — | — | |
| Bromide SCHEMBL4662619 | 0.72 | TSHR (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 705 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025242747-A1 | MULTI -COMPONENT FORMULATIONS OF ORGANOMETALLIC REAGENTS | MERCK PATENT GMBH (DE) | 2025-11-27 | — | — | WO | claimed |
| CN-118908996-A | A composition containing C (sp2) P bond or C (sp)3) Process for preparing organic phosphine compound of-P bond | 烟台大学 | 2024-11-08 | — | — | CN | claimed |
| CN-114181142-B | Synthesis method of 6- (4-methylpiperazine-1-yl) -4-o-tolylpropionic nicotinamide | 浙江工业大学 | 2023-10-20 | — | — | CN | claimed |
| CN-113620869-B | Preparation method of betrixaban | 江西同和药业股份有限公司 | 2023-04-18 | — | — | CN | claimed |
| CN-113929885-B | Composite catalyst and application thereof in preparation of glycolide | 江苏金之虹新材料有限公司 | 2023-01-20 | — | — | CN | claimed |
| CN-114181142-A | Synthetic method of 6- (4-methylpiperazine-1-yl) -4-o-tolylnicotinamide | 浙江工业大学 | 2022-03-15 | — | — | CN | claimed |
| CN-113929885-A | Composite catalyst and application thereof in preparation of glycolide | 江苏金之虹新材料有限公司 | 2022-01-14 | — | — | CN | claimed |
| CN-113620869-A | Preparation method of betrixaban | 江西同和药业股份有限公司 | 2021-11-09 | — | — | CN | claimed |
| WO-2021012479-A1 | HYDROGENATED CYCLIC [8] AROMATIC HYDROCARBON COMPOUND AND PREPARATION METHOD THEREFOR | 清华大学 | 2021-01-28 | — | — | WO | claimed |
| WO-2021012478-A1 | HYDROGENATION ANNULE [12] AROMATIC COMPOUND AND PREPARATION METHOD THEREFOR | 清华大学 | 2021-01-28 | — | — | WO | claimed |
| WO-2004062622-A2 | PROCESS OF PREPARING ESTERS AND ETHERS OF PROBUCOL AND DERIVATIVES THEREOF | ATHEROGENICS, INC. (US) | 2004-07-29 | — | — | WO | claimed |
| EP-0977739-B1 | SYNTHESIS OF INTERMEDIATES USEFUL IN PREPARING TRICYCLIC COMPOUNDS | SCHERING CORP (US) | 2003-10-29 | — | — | EP | claimed |
| US-6458962-B1 | VIRICIDES FOR TREATMENT OF AIDS AND HYDROGENATION OF COMPOUNDS | THE UNIVERSITY OF TENNESSEEE RESEARCH CORPORATION | 2002-10-01 | — | — | US | claimed |
| US-20010034459-A1 | Process for preparing 4'-trifluoromethyl-2-methylbiphenyl and 4'-trifluoromethyl-biphenyl-2-carboxylic acid from o-tolylmetallates | MEUDT ANDREAS (DE) | 2001-10-25 | — | — | US | claimed |
| EP-1120397-A2 | Process for preparing triazole derivative | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2001-08-01 | — | — | EP | claimed |
| EP-1112991-A2 | Process for the preparation of 4'-trifluoromethyl-2-methylbiphenyl and 4'-trifluoromethylbiphenyl-2-carboxylic acid from o-tolylmetallates | Clariant GmbH (DE) | 2001-07-04 | — | — | EP | claimed |
| WO-2000056332-A1 | SULTAMS: CATALYST SYSTEMS FOR ASYMMETRIC REDUCTION OF A C=N INTERMEDIATE BIOLOGICAL COMPOSITIONS AND METHODS FOR MAKING THE SULTAMS | THE UNIVERSITY OF TENNESSEE RESEARCH CORPORATION (US) | 2000-09-28 | — | — | WO | claimed |
| US-5998620-A | Synthesis of intermediates useful in preparing tricyclic compounds | SCHERING CORPORATION (US) | 1999-12-07 | — | — | US | claimed |
| US-5623087-A | Method for preparation of optically active diarylalanines | NDSU-RESEARCH FOUNDATION (US) | 1997-04-22 | — | — | US | claimed |
| EP-0704419-A1 | PROCESS FOR PRODUCING TRIAZOLE DERIVATIVE | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1996-04-03 | — | — | EP | claimed |