Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3929886 | 0.73 | BACE1 (0.60) | ALDH1A1SMN1; SMN2HTTMAPTTP53 | |
| SCHEMBL9596069 | 0.72 | BACE1 (0.41) | ALDH1A1SMN1; SMN2HTTMAPTTSHR | |
| SCHEMBL7062972 | 0.71 | SLC1A3 (0.56) | ALDH1A1SMN1; SMN2HTTMAPTTP53 | |
| SCHEMBL28459125 | 0.67 | CYP2C9 (0.55) | ALDH1A1SMN1; SMN2MAPTTSHRMEN1 | |
| SCHEMBL6933312 | 0.67 | PKM (0.51) | ALDH1A1SMN1; SMN2MAPTTP53TSHR | |
| SCHEMBL30856551 | 0.67 | SLC1A3 (0.62) | ALDH1A1SMN1; SMN2HTTTP53TSHR | |
| Hydrochloric Acid SCHEMBL7346258 | 0.67 | BACE1 (0.48) | SMN1; SMN2HTTMAPTTSHRKMT2A | |
| Hydrochloric Acid SCHEMBL7346261 | 0.67 | BACE1 (0.48) | SMN1; SMN2HTTMAPTTSHRKMT2A | |
| SCHEMBL2735619 | 0.67 | TSHR (0.70) | ALDH1A1SMN1; SMN2HTTMAPTTP53 | |
| SCHEMBL6589504 | 0.66 | SLC1A3 (0.54) | ALDH1A1SMN1; SMN2HTTMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993015047-A1 | AMINO ACID DERIVATIVES AS PAF ANTAGONISTS | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1993-08-05 | — | — | WO | claimed |
| WO-1993015047-A1 | AMINO ACID DERIVATIVES AS PAF ANTAGONISTS | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1993-08-05 | — | — | WO | disclosed |