Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 3/20 | 0.41 |
| ▸ | CTSS | P25774 | 3/20 | 0.41 |
| ▸ | CTSK | P43235 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP7 | P09237 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7061397 | 0.87 | MMP2 (0.51) | KMT2AMEN1CYP2C9CTSLCTSS | |
| SCHEMBL9596098 | 0.74 | TDP1 (0.54) | BACE1KMT2AMEN1CYP2C9ALDH1A1 | |
| SCHEMBL7060922 | 0.73 | MMP2 (0.48) | KMT2AMEN1CYP2C9CTSLCTSS | |
| SCHEMBL24855401 | 0.72 | CTSK (0.57) | CTSLCTSSCTSKMMP1MMP2 | |
| SCHEMBL18775046 | 0.72 | CTSK (0.57) | CTSLCTSSCTSKMMP1MMP2 | |
| SCHEMBL6795703 | 0.72 | CTSL (0.53) | BACE1KMT2AMEN1CTSLCTSS | |
| SCHEMBL9596076 | 0.72 | ALDH1A1 (0.46) | KMT2AMEN1CYP2C9TSHRMAPT | |
| SCHEMBL16388801 | 0.71 | CTSL (0.57) | CTSLCTSSCTSKLARS1MMP1 | |
| SCHEMBL8998137 | 0.71 | BACE1 (0.50) | BACE1KMT2AMEN1CTSLCTSS | |
| SCHEMBL8133560 | 0.71 | MMP1 (0.51) | BACE1KMT2AMEN1CYP2C9CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993015047-A1 | AMINO ACID DERIVATIVES AS PAF ANTAGONISTS | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1993-08-05 | — | — | WO | claimed |
| WO-1993015047-A1 | AMINO ACID DERIVATIVES AS PAF ANTAGONISTS | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1993-08-05 | — | — | WO | disclosed |
| WO-1993006092-A1 | PIPERAZINYL (SULFONYL)AMIDE DERIVATIVES OF CAMPHOR AS OXYTOCIN ANTAGONISTS | MERCK & CO., INC. (US) | 1993-04-01 | — | — | WO | disclosed |