SCHEMBL9596090

SCHEMBL9596090

NNc1cc(F)ccc1[N+](=O)[O-]

nearest known ligand 0.58

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.58
ATM Q13315 1/20 0.58
PDE7A Q13946 1/20 0.46
ALDH1A1 P00352 5/20 0.41
MAPT P10636 3/20 0.41
KCNMA1 Q12791 1/20 0.41
MAPK1 P28482 1/20 0.41
EPAS1 Q99814 1/20 0.41
HSPB1 P04792 2/20 0.41
TSHR P16473 1/20 0.40
HTT P42858 1/20 0.40
RAB9A P51151 1/20 0.40
GAA P10253 2/20 0.39
POLB P06746 1/20 0.39
HIF1A Q16665 1/20 0.39
HTR6 P50406 2/20 0.39
GLA P06280 1/20 0.38
ALDH3A1 P30838 1/20 0.38
KAT2B Q92831 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9208634 0.84 TDP1 (0.52) TDP1ATMPDE7AALDH1A1MAPT
SCHEMBL1360573 0.81 TDP1 (0.58) TDP1ATMPDE7AALDH1A1MAPT
SCHEMBL503378 0.81 TDP1 (0.58) TDP1ATMALDH1A1MAPTKCNMA1
SCHEMBL29705127 0.81 TDP1 (0.58) TDP1ATMALDH1A1MAPTKCNMA1
SCHEMBL29702896 0.79 TDP1 (0.55) TDP1ALDH1A1MAPTMAPK1TSHR
SCHEMBL9387603 0.79 TDP1 (0.55) TDP1ALDH1A1MAPTMAPK1TSHR
SCHEMBL30378593 0.79 ALDH1A1 (0.59) TDP1ATMALDH1A1MAPTMAPK1
SCHEMBL2508268 0.79 ALDH1A1 (0.59) TDP1ATMALDH1A1MAPTMAPK1
SCHEMBL35212456 0.78 TDP1 (0.50) TDP1ATMPDE7AALDH1A1MAPT
SCHEMBL437440 0.78 TSHR (0.58) TDP1PDE7AALDH1A1MAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1021191-C SUBSTITUTED 3-(4-NITROPHENOXY) PYRAZOLES HERBICIDES COMPOSITION MONSANTO CO (US) 1993-06-16 CN disclosed
US-5185025-A SUBSTITUTED PYRAZOLES AND THEIR USE AS HERBICIDES MONSANTO COMPANY (US) 1993-02-09 US disclosed
US-5045106-A 3-phenoxypyrazole MONSANTO COMPANY (US) 1991-09-03 US disclosed
US-4964895-A Substituted 4-(4-nitrophenoxy) pyrazoles and their use as herbicides MONSANTO COMPANY (US) 1990-10-23 US disclosed
EP-0371947-A1 Substituted pyrazoles and their use as herbicides Monsanto Company (US) 1990-06-06 EP disclosed
EP-0370990-A1 Herbicidal substituted pyrazoles MONSANTO COMPANY (US) 1990-05-30 EP disclosed
CN-1033457-A 3-(4-nitrophenoxy) pyrazoles that replaces and as the purposes of weedicide MONSANTO CO (US) 1989-06-21 CN disclosed
EP-0295233-A2 Substituted 3-(4-nitrophenoxy)pyrazoles and their use as herbicides Monsanto Company (US) 1988-12-14 EP disclosed