Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | MERTK | Q12866 | 1/20 | 0.44 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2508268 | 1.00 | ALDH1A1 (0.59) | ALDH1A1HTTRAB9AALDH3A1TDP1 | |
| SCHEMBL28738890 | 0.91 | EPAS1 (0.55) | ALDH1A1HTTRAB9AALDH3A1TDP1 | |
| SCHEMBL5496871 | 0.90 | TDP1 (0.65) | ALDH1A1HTTRAB9AALDH3A1TDP1 | |
| SCHEMBL2507274 | 0.88 | EPAS1 (0.58) | ALDH1A1HTTRAB9AALDH3A1TDP1 | |
| SCHEMBL2211997 | 0.87 | L3MBTL1 (0.56) | ALDH1A1HTTRAB9AALDH3A1TDP1 | |
| SCHEMBL11901468 | 0.87 | HTT (0.61) | ALDH1A1HTTRAB9AALDH3A1TDP1 | |
| SCHEMBL31144749 | 0.87 | ALDH1A1 (0.54) | ALDH1A1HTTRAB9AALDH3A1TDP1 | |
| SCHEMBL8938805 | 0.87 | MAPT (0.61) | ALDH1A1HTTRAB9AALDH3A1TDP1 | |
| SCHEMBL16634661 | 0.87 | HCAR3 (0.57) | ALDH1A1HTTRAB9ATDP1MEN1 | |
| SCHEMBL16634663 | 0.87 | HCAR3 (0.57) | ALDH1A1HTTRAB9ATDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118119612-A | Novel compounds and pharmaceutical compositions comprising the same | 萨皮恩斯生物有限公司 | 2024-05-31 | — | — | CN | disclosed |
| WO-2023239227-A1 | NOVEL COMPOUND, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT | 주식회사 사피엔스바이오 | 2023-12-14 | — | — | WO | disclosed |