Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 8/20 | 0.71 |
| ▸ | DRD2 | P14416 | 8/20 | 0.71 |
| ▸ | HTR2A | P28223 | 8/20 | 0.71 |
| ▸ | HTR7 | P34969 | 1/20 | 0.69 |
| ▸ | HTR6 | P50406 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9594521 | 0.99 | HTR1A (0.70) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL9595844 | 0.94 | DRD2 (0.67) | HTR1ADRD2HTR2AHTR7HTR6 | |
| Hydrochloric Acid SCHEMBL9377059 | 0.93 | DRD2 (0.66) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL9601759 | 0.91 | HTR1A (0.70) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL30649298 | 0.91 | HTR1A (0.70) | HTR1ADRD2HTR2AHTR7HTR6 | |
| Hydrochloric Acid SCHEMBL9382359 | 0.90 | HTR1A (0.69) | HTR1ADRD2HTR2AHTR7HTR6 | |
| Hydrochloric Acid SCHEMBL9595406 | 0.89 | HTR1A (0.71) | HTR1ADRD2HTR2AHTR7HTR6 | |
| Hydrochloric Acid SCHEMBL9379578 | 0.89 | HTR1A (0.71) | HTR1ADRD2HTR2AHTR7HTR6 | |
| Hydrochloric Acid SCHEMBL9376327 | 0.88 | HTR1A (0.66) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL8831786 | 0.85 | HTR1A (0.74) | HTR1ADRD2HTR2AHTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993016073-A1 | PIPERAZINE AND PIPERIDINE DERIVATIVES, AND THEIR USE AS ANTIPSYCHOTICS | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-08-19 | — | — | WO | claimed |
| WO-1993016073-A1 | PIPERAZINE AND PIPERIDINE DERIVATIVES, AND THEIR USE AS ANTIPSYCHOTICS | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-08-19 | — | — | WO | disclosed |