SCHEMBL9596266

SCHEMBL9596266

c1ccc(Oc2ccn[nH]2)cc1

nearest known ligand 0.56

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 9/20 0.56
SCN4A P35499 3/20 0.56
NPC1 O15118 2/20 0.56
RAB9A P51151 2/20 0.56
TSHR P16473 1/20 0.46
KDM4E B2RXH2 2/20 0.46
HAO1 Q9UJM8 1/20 0.42
KMT2A Q03164 2/20 0.39
ATM Q13315 1/20 0.39
NISCH Q9Y2I1 1/20 0.37
NR1H2 P55055 1/20 0.37
BAX Q07812 1/20 0.37
MAOA P21397 1/20 0.37
MAPT P10636 2/20 0.36
GLA P06280 1/20 0.36
TNK2 Q07912 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28690610 0.83 PDPK1 (0.43) LTA4HSCN4ANPC1RAB9AKDM4E
SCHEMBL11495461 0.72 LTA4H (0.50) LTA4HSCN4ANPC1RAB9ATSHR
SCHEMBL3664310 0.70 SCN4A (0.36) LTA4HSCN4ANPC1RAB9AKDM4E
SCHEMBL3944046 0.69 LTA4H (0.43) LTA4HSCN4ARAB9ATSHRKDM4E
SCHEMBL4266196 0.69 LTA4H (0.58) LTA4HTSHRKDM4EHAO1KMT2A
SCHEMBL7054133 0.67
SCHEMBL11691824 0.67
SCHEMBL7199146 0.67
Diphenylether SCHEMBL8462019 0.67 LTA4H (0.86) LTA4HSCN4ANPC1RAB9ATSHR
Diphenylether SCHEMBL8157951 0.67 LTA4H (0.86) LTA4HSCN4ANPC1RAB9ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118974034-A Pest control agent 日本化药株式会社 2024-11-15 CN disclosed
CN-114728912-A MTA-synergistic PRMT5 inhibitors 米拉蒂医疗股份有限公司 2022-07-08 CN disclosed
US-5185025-A SUBSTITUTED PYRAZOLES AND THEIR USE AS HERBICIDES MONSANTO COMPANY (US) 1993-02-09 US disclosed
US-4964895-A Substituted 4-(4-nitrophenoxy) pyrazoles and their use as herbicides MONSANTO COMPANY (US) 1990-10-23 US disclosed
EP-0371947-A1 Substituted pyrazoles and their use as herbicides Monsanto Company (US) 1990-06-06 EP disclosed
EP-0295233-A2 Substituted 3-(4-nitrophenoxy)pyrazoles and their use as herbicides Monsanto Company (US) 1988-12-14 EP disclosed