SCHEMBL4266196

SCHEMBL4266196

c1ccc(Oc2ccc(Oc3ccccc3)[nH]2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 5/20 0.58
TSHR P16473 1/20 0.58
MAOA P21397 2/20 0.44
NR1H2 P55055 1/20 0.44
BAX Q07812 1/20 0.44
HAO1 Q9UJM8 1/20 0.40
MAOB P27338 2/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA4 P22748 1/20 0.39
HTR1A P08908 1/20 0.38
SLC6A2 P23975 1/20 0.38
SLC6A4 P31645 1/20 0.38
SLC6A3 Q01959 1/20 0.38
NTRK1 P04629 1/20 0.38
IGF1R P08069 1/20 0.38
FGFR1 P11362 1/20 0.38
NTRK3 Q16288 1/20 0.38
NTRK2 Q16620 1/20 0.38
KDM4E B2RXH2 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20708902 0.84 LTA4H (0.46) LTA4HTSHRMAOANR1H2BAX
SCHEMBL22185814 0.77 BRD4 (0.41) LTA4HTSHRNTRK1IGF1RFGFR1
SCHEMBL31304048 0.76 PGR (0.42) LTA4HTSHRMAOAMAOBCA1
Diphenylether SCHEMBL4950525 0.75 LTA4H (1.00) LTA4HTSHRMAOANR1H2BAX
Diphenylether SCHEMBL2461810 0.75 LTA4H (1.00) LTA4HTSHRMAOANR1H2BAX
Diphenylether SCHEMBL9061108 0.75 LTA4H (1.00) LTA4HTSHRMAOANR1H2BAX
Diphenylether SCHEMBL12286 0.75 LTA4H (1.00) LTA4HTSHRMAOANR1H2BAX
SCHEMBL11160321 0.74 LTA4H (0.41) LTA4HTSHRMAOANR1H2BAX
SCHEMBL31304013 0.73 PSIP1 (0.41) LTA4HTSHRCA1CA2SOS1
SCHEMBL79800 0.72 LTA4H (0.50) LTA4HTSHRMAOANR1H2BAX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116057642-A Hydrated porous material and method for preparing same 法国原子能源和替代能源委员会 2023-05-02 CN claimed
CN-116057642-A Hydrated porous material and method for preparing same 法国原子能源和替代能源委员会 2023-05-02 CN disclosed
US-7605215-B2 Process for producing olefin copolymerization catalyst and process for producing olefin copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-10-20 US disclosed
EP-2066727-A1 POLYCARBONATE-POLYSILOXANE COPOLYMERS, METHOD OF MAKING, AND ARTICLES FORMED THEREFROM Sabic Innovative Plastics IP B.V. (NL) 2009-06-10 EP disclosed
US-20080227937-A1 Process for Producing Olefin Copolymerization Catalyst and Process for Producing Olefin Copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-09-18 US disclosed
WO-2008042500-A1 POLYCARBONATE-POLYSILOXANE COPOLYMERS, METHOD OF MAKING, AND ARTICLES FORMED THEREFROM SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-04-10 WO disclosed
US-4337999-A MIXTURES WITH A COUMARIN FLUORESCENT DYE; SELF-LUMINESCENT; LOW VOLTAGE SHARP CORPORATION (JP) 1982-07-06 US disclosed