Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | MC4R | P32245 | 1/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.49 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
| ▸ | CCR5 | P51681 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL48088 | 1.00 | CYP2D6 (0.61) | CYP2D6MC4ROPRM1OPRK1OPRL1 | |
| SCHEMBL2916607 | 1.00 | CYP2D6 (0.61) | CYP2D6MC4ROPRM1OPRK1OPRL1 | |
| Ethane SCHEMBL9682617 | 0.98 | CYP2D6 (0.59) | CYP2D6MC4ROPRM1OPRK1OPRL1 | |
| Fumaric Acid SCHEMBL9596362 | 0.88 | CYP2D6 (0.49) | CYP2D6MC4ROPRM1OPRK1OPRL1 | |
| Maleic Acid SCHEMBL9596354 | 0.88 | CYP2D6 (0.49) | CYP2D6MC4ROPRM1OPRK1OPRL1 | |
| SCHEMBL5275767 | 0.85 | CYP2D6 (0.58) | CYP2D6MC4ROPRM1OPRK1OPRL1 | |
| SCHEMBL9137138 | 0.85 | CYP2D6 (0.58) | CYP2D6MC4ROPRM1OPRK1OPRL1 | |
| SCHEMBL6097455 | 0.83 | CYP2D6 (0.65) | CYP2D6MC4ROPRM1OPRK1OPRL1 | |
| SCHEMBL2916278 | 0.82 | HSD11B1 (0.46) | CYP2D6OPRM1HSD11B1 | |
| SCHEMBL19614197 | 0.81 | CYP2D6 (0.68) | CYP2D6MC4ROPRM1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090111992-A1 | ALKYL ETHER DERIVATIVES OR SALTS THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2009-04-30 | — | — | US | disclosed |
| US-20090111992-A1 | ALKYL ETHER DERIVATIVES OR SALTS THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2009-04-30 | — | — | US | disclosed |
| US-5183902-A | Muscle relaxants | A. H. ROBINS COMPANY, INCORPORATED (US) | 1993-02-02 | — | — | US | disclosed |
| US-5151418-A | Muscle relaxants | A. H. ROBINS COMPANY, INCORPORATED (US) | 1992-09-29 | — | — | US | disclosed |
| US-5130309-A | Cardiovascular disorders | A. H. ROBINS COMPANY, INCORPORATED (US) | 1992-07-14 | — | — | US | disclosed |
| US-5096873-A | Containign a support, color developer layer with a basic leuco dye in it; high density speed recording, image storage stability | JUJO PAPER CO., LTD. (JP) | 1992-03-17 | — | — | US | disclosed |
| US-5068231-A | Ureas and thioureas for relaxing muscles | A. H. ROBINS COMPANY INCORPORATED (US) | 1991-11-26 | — | — | US | disclosed |
| US-4956359-A | CARBOXAMIDES OR THIOCARBOXAMIDES OF ARYL OXY OR THIO AZETIDINES | A. H. ROBINS COMPANY, INC. (US) | 1990-09-11 | — | — | US | disclosed |
| EP-0194112-B1 | 3-ARYL-OXYAZETIDINECARBOXAMIDES HAVING ANTI-MUSCLE TENSION, ANTI-MUSCLE SPASTICITY, ANTICONVULSANT AND ANTIEPILECTIC ACTIVITY | A.H. ROBINS COMPANY, INCORPORATED (US) | 1990-05-23 | — | — | EP | disclosed |
| EP-0102740-B1 | N-FORMYL AND N-HYDROXYMETHYL-3-PHENOXY-1-AZETIDINECARBOXAMIDES AND THEIR PREPARATION AND USE | A.H. ROBINS COMPANY, INCORPORATED (US) | 1986-11-05 | — | — | EP | disclosed |
| US-4571393-A | ANTICONVULSANT TREATMENT FOR MAMMALS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1986-02-18 | — | — | US | disclosed |
| US-4505907-A | ANTICONVULSANTS | A. H. ROBINS COMPANY, INC. (US) | 1985-03-19 | — | — | US | disclosed |
| EP-0102740-A1 | N-formyl and n-hydroxymethyl-3-phenoxy-1-azetidinecarboxamides and their preparation and use | A.H. ROBINS COMPANY, INCORPORATED (US) | 1984-03-14 | — | — | EP | disclosed |
| EP-0102194-A1 | 3-Phenoxy-1-azetidinecarboxamides and their use and preparation | A.H. ROBINS COMPANY, INCORPORATED (US) | 1984-03-07 | — | — | EP | disclosed |
| US-4379151-A | 3-Phenoxyazetidines for anorexigenic activity | A. H. ROBINS COMPANY, INC. (US) | 1983-04-05 | — | — | US | disclosed |
| US-4324791-A | DERIVATIVES OF 3,3-DIPHENYL-2-PYRROLIDINONES | A. H. ROBINS COMPANY, INC. (US) | 1982-04-13 | — | — | US | disclosed |
| US-4260606-A | ANTIDEPRESSANTS | A. H. ROBINS COMPANY, INC. (US) | 1981-04-07 | — | — | US | disclosed |
| US-4144245-A | 4-Hydroxymethyl-2-pyrrolidinones | A. H. ROBINS COMPANY, INC. (US) | 1979-03-13 | — | — | US | disclosed |
| US-4133881-A | Azetidinyl acetonitrile and acetamide antiarrhythmia compositions and methods | A. H. ROBINS COMPANY, INCORPORATED (US) | 1979-01-09 | — | — | US | disclosed |
| US-4120969-A | ANALGETIC, ANTIDIARRHEAL ACTIVITY | A. H. ROBINS COMPANY, INCORPORATED (US) | 1978-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090111992-A1 | ALKYL ETHER DERIVATIVES OR SALTS THEREOF | AHNAK, NGF, PMP22 | CYP2D6 4089/4885MC4R 4649/4885OPRM1 1485/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.