Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9396263 | 0.83 | ALDH1A1 (0.50) | ALDH1A1ATMHCAR2TSHRHPGD | |
| SCHEMBL28836165 | 0.83 | HCAR2 (0.50) | ALDH1A1ATMHCAR2TSHRHPGD | |
| Hydrochloric Acid SCHEMBL11686455 | 0.82 | HCAR2 (0.48) | ALDH1A1ATMHCAR2TSHRHPGD | |
| SCHEMBL11686451 | 0.82 | ALDH1A1 (0.48) | ALDH1A1ATMHCAR2TSHRHPGD | |
| SCHEMBL11747354 | 0.81 | ALDH1A1 (0.58) | ALDH1A1ATMHCAR2TSHRHPGD | |
| SCHEMBL8908162 | 0.80 | CHRNB2 (0.58) | ALDH1A1ATMHCAR2TSHRHPGD | |
| SCHEMBL13398589 | 0.79 | EPHX1 (0.47) | ALDH1A1ATMHCAR2TSHRHPGD | |
| SCHEMBL3630997 | 0.77 | ALDH1A1 (0.44) | ALDH1A1ATMHCAR2TSHRHPGD | |
| Acetic Acid Butyl Ester SCHEMBL11877125 | 0.77 | ALDH1A1 (0.78) | ALDH1A1ATMHCAR2TSHRHPGD | |
| SCHEMBL10918173 | 0.77 | ALDH1A1 (0.52) | ALDH1A1ATMHCAR2TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993011128-A1 | AMINOALKYLPYRROLIDINYLTHIOCARBAPENEM DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-06-10 | — | — | WO | disclosed |
| US-4001424-A | 1-Oxo-1H-naphtho [2,1-b] pyran derivatives for treating depression | CARLO ERBA S.P.A. (IT) | 1977-01-04 | — | — | US | disclosed |