Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 12/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 12/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9597943 | 0.86 | HDAC1 (0.43) | HDAC1HDAC6HDAC8HDAC3HDAC2 | |
| SCHEMBL9597263 | 0.85 | KMT2A (0.47) | HDAC1HDAC6HDAC8HDAC3HDAC2 | |
| SCHEMBL9597803 | 0.85 | HDAC1 (0.57) | HDAC1HDAC6HDAC8HDAC3HDAC2 | |
| SCHEMBL9029836 | 0.84 | HDAC1 (0.53) | HDAC1HDAC6HDAC8HDAC3HDAC2 | |
| SCHEMBL9598347 | 0.84 | HDAC1 (0.51) | HDAC1HDAC6HDAC8HDAC3HDAC2 | |
| SCHEMBL9597414 | 0.82 | HDAC1 (0.56) | HDAC1HDAC6HDAC8HDAC3HDAC2 | |
| SCHEMBL9603314 | 0.81 | HDAC1 (0.52) | HDAC1HDAC6HDAC8HDAC3HDAC2 | |
| SCHEMBL9597572 | 0.80 | OPRM1 (0.47) | HDAC1HDAC6HDAC8HDAC3HDAC2 | |
| SCHEMBL9597526 | 0.80 | ALDH1A1 (0.51) | HDAC1HDAC6HDAC8HDAC3HDAC2 | |
| SCHEMBL9597228 | 0.80 | HDAC1 (0.56) | HDAC1HDAC6HDAC8HDAC3HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5256789-A | Antiinflammatory hydroxamic acids and N-hydroxyureas | PFIZER INC. (US) | 1993-10-26 | — | — | US | disclosed |