Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.68 |
| ▸ | POLB | P06746 | 4/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12329335 | 0.84 | KDM4E (0.65) | KDM4EALDH1A1POLBTDP1L3MBTL1 | |
| SCHEMBL22529080 | 0.83 | KDM4E (0.63) | KDM4EALDH1A1POLBTDP1L3MBTL1 | |
| SCHEMBL9376686 | 0.83 | KDM4E (0.63) | KDM4EALDH1A1POLBTDP1L3MBTL1 | |
| SCHEMBL9570185 | 0.83 | KDM4E (0.68) | KDM4EALDH1A1POLBTDP1L3MBTL1 | |
| SCHEMBL8172945 | 0.83 | KDM4E (0.63) | KDM4EALDH1A1POLBTDP1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL31312583 | 0.81 | KDM4E (0.61) | KDM4EALDH1A1POLBTDP1L3MBTL1 | |
| SCHEMBL10513383 | 0.81 | KDM4E (0.78) | KDM4EALDH1A1POLBTDP1L3MBTL1 | |
| SCHEMBL4446188 | 0.81 | KDM4E (1.00) | KDM4EALDH1A1POLBTDP1L3MBTL1 | |
| SCHEMBL976011 | 0.79 | METTL3 (0.47) | KDM4EALDH1A1POLBTDP1L3MBTL1 | |
| SCHEMBL9451883 | 0.79 | KDM4E (0.62) | KDM4EALDH1A1POLBTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5270322-A | Imidazo[1,2-a]pyridines, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1993-12-14 | — | — | US | disclosed |