Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.55 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.55 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.55 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.55 |
| ▸ | NPY1R | P25929 | 1/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | ATM | Q13315 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL618092 | 0.99 | MAPT (0.54) | RAB9AMAPTSMN1; SMN2NPC1HTT | |
| SCHEMBL8510497 | 0.84 | KMT2A (0.49) | MAPTALDH1A1POLBKDM4EHSD17B10 | |
| SCHEMBL3475677 | 0.83 | KMT2A (0.48) | MAPTALDH1A1POLBKDM4EHSD17B10 | |
| SCHEMBL6120513 | 0.83 | KMT2A (0.48) | MAPTALDH1A1POLBKDM4EHSD17B10 | |
| SCHEMBL620485 | 0.83 | GABRP (0.66) | MAPTSMN1; SMN2HTTALDH1A1LMNA | |
| SCHEMBL4058993 | 0.81 | SMN1; SMN2 (0.47) | RAB9AMAPTSMN1; SMN2NPC1HTT | |
| SCHEMBL9598974 | 0.81 | ADORA1 (0.44) | RAB9AMAPTSMN1; SMN2NPC1HTT | |
| SCHEMBL9599417 | 0.80 | KDM4E (0.57) | RAB9AMAPTSMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL9598196 | 0.79 | ADORA1 (0.43) | MAPTSMN1; SMN2NPC1HTTALDH1A1 | |
| SCHEMBL9597904 | 0.78 | BPTF (0.46) | MAPTHTTALDH1A1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013104-A1 | C.N.S. ACTIVE TRICYCLIC THIENOPYRIDINE DERIVATIVES | SMITHKLINE BEECHAM PLC (GB) | 1993-07-08 | — | — | WO | disclosed |