Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.57 |
| ▸ | MAPT | P10636 | 7/20 | 0.57 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.57 |
| ▸ | RAD52 | P43351 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 6/20 | 0.48 |
| ▸ | GAA | P10253 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9598196 | 0.87 | ADORA1 (0.43) | KDM4EALDH1A1MAPTADORA1RAD52 | |
| SCHEMBL9597904 | 0.86 | BPTF (0.46) | KDM4EALDH1A1MAPTADORA1RAD52 | |
| SCHEMBL9598034 | 0.85 | PRKCI (0.48) | KDM4EALDH1A1MAPTADORA1RAD52 | |
| SCHEMBL9603759 | 0.85 | GABRP (0.41) | KDM4EALDH1A1MAPTADORA1RAD52 | |
| SCHEMBL618092 | 0.81 | MAPT (0.54) | KDM4EALDH1A1MAPTKMT2ALMNA | |
| SCHEMBL9598331 | 0.81 | ADORA1 (0.64) | KDM4EMAPTADORA1 | |
| SCHEMBL9597948 | 0.80 | RAB9A (0.55) | KDM4EALDH1A1MAPTKMT2ALMNA | |
| SCHEMBL9598974 | 0.77 | ADORA1 (0.44) | KDM4EALDH1A1MAPTADORA1LMNA | |
| SCHEMBL8289394 | 0.74 | ADORA1 (1.00) | KDM4EALDH1A1MAPTADORA1RAD52 | |
| SCHEMBL9599408 | 0.73 | KDM4E (0.44) | KDM4EALDH1A1MAPTHPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013104-A1 | C.N.S. ACTIVE TRICYCLIC THIENOPYRIDINE DERIVATIVES | SMITHKLINE BEECHAM PLC (GB) | 1993-07-08 | — | — | WO | disclosed |