Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 3/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | NPY1R | P25929 | 1/20 | 0.47 |
| ▸ | NPY2R | P49146 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ACACB | O00763 | 4/20 | 0.42 |
| ▸ | ACACA | Q13085 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9598511 | 1.00 | ADRB2 (0.48) | ADRB2ADRB1CYP2D6NR3C1ADRA1A | |
| SCHEMBL8892157 | 0.83 | ADRB1 (0.66) | ADRB2ADRB1CYP2D6NR3C1ADRA1A | |
| SCHEMBL13675777 | 0.82 | S1PR1 (0.51) | KMT2AALDH1A1 | |
| SCHEMBL19944374 | 0.79 | ADRB2 (0.48) | ADRB2ADRB1CYP2D6NR3C1ADRA1A | |
| SCHEMBL10721624 | 0.77 | CYP2D6 (0.39) | ADRB2ADRB1CYP2D6KMT2AMMP12 | |
| SCHEMBL10720250 | 0.77 | CYP2D6 (0.39) | ADRB2ADRB1CYP2D6KMT2AMMP12 | |
| SCHEMBL19944440 | 0.77 | ADRB2 (0.56) | ADRB2ADRB1CYP2D6NR3C1ADRA1A | |
| SCHEMBL19944439 | 0.76 | ADRB2 (0.48) | ADRB2ADRB1CYP2D6NR3C1ADRA1A | |
| SCHEMBL19483271 | 0.75 | AR (0.50) | NPSR1ARKMT2APOLBMAPT | |
| SCHEMBL19944672 | 0.74 | ADRB1 (0.73) | ADRB2ADRB1CYP2D6NR3C1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5190867-A | Process for the preparation of R-2,2-R1,R2 -1,3-dioxolane-4-methanol | SHELL INTERNATIONAL PETROLEUM COMPANY, LTD. (GB) | 1993-03-02 | — | — | US | disclosed |
| EP-0244912-B1 | A PROCESS FOR THE PREPARATION OF R AND S-2,2-R1,R2-1,3-DIOXOLANE-4-METHANOL | GIST-BROCADES N.V. (NL) | 1990-06-27 | — | — | EP | disclosed |