Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KIF20A | O95235 | 1/20 | 0.32 |
| ▸ | CLK1 | P49759 | 1/20 | 0.32 |
| ▸ | CLK2 | P49760 | 1/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9038722 | 0.86 | MAPT (0.43) | GAAMAPTKDM4ECYP1A2CYP2C9 | |
| SCHEMBL9038730 | 0.86 | MAPT (0.43) | GAAMAPTKDM4ECYP1A2CYP2C9 | |
| SCHEMBL9597473 | 0.82 | MAPT (0.41) | GAAMAPTKDM4ECYP1A2CYP2C9 | |
| SCHEMBL9595515 | 0.80 | MAPT (0.48) | GAAMAPTKDM4ECYP1A2CYP2C9 | |
| SCHEMBL9599145 | 0.79 | PPIA (0.43) | — | |
| SCHEMBL9596670 | 0.78 | HTT (0.46) | MAPTCYP1A2CYP2C19LMNAMAPK1 | |
| SCHEMBL10993495 | 0.74 | GAA (0.32) | GAAMAPTMEN1LMNAKMT2A | |
| SCHEMBL4318524 | 0.72 | GAA (0.43) | GAAMAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL4318522 | 0.72 | GAA (0.43) | GAAMAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL9595934 | 0.72 | KMT2A (0.45) | GAAMAPTKDM4ENPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993016076-A1 | 3-(1H^_-TETRAZOL-5-YL)-4H^_-PYRIDO[1,2-A^_]PYRIMIDINE-4-ONES, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND THE PREPARATION THEREOF | CHINOIN GYÓGYSZER- ÉS VEGYÉSZETI TERMÉKEK GYÁRA RT. (HU) | 1993-08-19 | — | — | WO | disclosed |
| WO-1993016070-A1 | 3-(PYRIDYLAMINO)-2-(1H^_-TETRAZOL-5-YL)-ACRYLNITRILES AND A PROCESS FOR THE PREPARATION THEREOF | CHINOIN GYÓGYSZER- ÉS VEGYÉSZETI TERMÉKEK GYÁRA RT. (HU) | 1993-08-19 | — | — | WO | disclosed |