Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIA | P62937 | 15/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | GCK | P35557 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | PPIF | P30405 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9598095 | 0.80 | PPIA (0.48) | PPIAGRM5PPIF | |
| SCHEMBL9599085 | 0.79 | GAA (0.33) | — | |
| SCHEMBL9038730 | 0.78 | MAPT (0.43) | — | |
| SCHEMBL9038722 | 0.78 | MAPT (0.43) | — | |
| SCHEMBL9595515 | 0.74 | MAPT (0.48) | HPGD | |
| SCHEMBL9596670 | 0.74 | HTT (0.46) | PPIA | |
| SCHEMBL9597473 | 0.74 | MAPT (0.41) | — | |
| SCHEMBL8032303 | 0.70 | PPIA (0.59) | PPIAGRM5GCKLTA4HMAPK14 | |
| SCHEMBL4318524 | 0.69 | GAA (0.43) | HPGD | |
| SCHEMBL4318522 | 0.69 | GAA (0.43) | HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993016070-A1 | 3-(PYRIDYLAMINO)-2-(1H^_-TETRAZOL-5-YL)-ACRYLNITRILES AND A PROCESS FOR THE PREPARATION THEREOF | CHINOIN GYÓGYSZER- ÉS VEGYÉSZETI TERMÉKEK GYÁRA RT. (HU) | 1993-08-19 | — | — | WO | disclosed |