Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ERN1 | O75460 | 4/20 | 0.48 |
| ▸ | TLR2 | O60603 | 2/20 | 0.48 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.48 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.48 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.47 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.45 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.44 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.44 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | CDK4 | P11802 | 1/20 | 0.43 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.43 |
| ▸ | CCND1 | P24385 | 1/20 | 0.43 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | TLR4 | O00206 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13460592 | 0.90 | RAB9A (0.50) | RAB9AKMT2ATDP1L3MBTL1ERN1 | |
| SCHEMBL986050 | 0.83 | CCNB2 (0.62) | TDP1L3MBTL1ERN1TLR2TLR1 | |
| SCHEMBL31683746 | 0.83 | CCNB2 (0.62) | TDP1L3MBTL1ERN1TLR2TLR1 | |
| SCHEMBL9597698 | 0.82 | RAB9A (0.52) | RAB9AKMT2ATDP1L3MBTL1ERN1 | |
| SCHEMBL19511901 | 0.80 | ERN1 (0.60) | RAB9ATDP1ERN1TLR2TLR1 | |
| SCHEMBL31533115 | 0.79 | MAPT (0.56) | RAB9AKMT2ATDP1L3MBTL1ERN1 | |
| SCHEMBL415678 | 0.79 | MAPT (0.56) | RAB9AKMT2ATDP1L3MBTL1ERN1 | |
| SCHEMBL9599135 | 0.79 | RAB9A (0.49) | RAB9AKMT2ATDP1L3MBTL1TLR2 | |
| SCHEMBL31307781 | 0.77 | KMT2A (0.56) | RAB9AKMT2ATDP1L3MBTL1PTGER3 | |
| SCHEMBL10854605 | 0.76 | APP (0.60) | RAB9ACAPN1SPHK2SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5196422-A | Antiinflammatory agents, antiallergens | ICI PHARMA (FR) | 1993-03-23 | — | — | US | disclosed |
| US-5089513-A | Antiinflammatory agents; antiallergens; asthma; side effect reduction | ICI PHARMA (FR) | 1992-02-18 | — | — | US | disclosed |