Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.40 |
| ▸ | TLR4 | O00206 | 1/20 | 0.39 |
| ▸ | TLR2 | O60603 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9597698 | 0.84 | RAB9A (0.52) | RAB9AL3MBTL1KMT2ATDP1CAPN1 | |
| SCHEMBL3944635 | 0.80 | HPGD (0.49) | RAB9AKMT2ATLR2KDM4EPOLB | |
| SCHEMBL9599183 | 0.79 | RAB9A (0.55) | RAB9AL3MBTL1KMT2ATDP1CAPN1 | |
| SCHEMBL16161550 | 0.75 | SMN1; SMN2 (0.49) | RAB9AL3MBTL1TLR2KDM4EPOLB | |
| SCHEMBL13460592 | 0.75 | RAB9A (0.50) | RAB9AL3MBTL1KMT2ATDP1CAPN1 | |
| SCHEMBL14172740 | 0.74 | KDM4E (0.60) | RAB9AKMT2ATLR2KDM4EPOLB | |
| SCHEMBL1050281 | 0.73 | CCNB2 (0.59) | RAB9AL3MBTL1KMT2ATDP1PTGER3 | |
| SCHEMBL11452343 | 0.72 | CCNB2 (0.59) | RAB9AL3MBTL1KMT2ATDP1PTGER3 | |
| SCHEMBL31307781 | 0.72 | KMT2A (0.56) | RAB9AL3MBTL1KMT2ATDP1PTGER3 | |
| SCHEMBL26731689 | 0.71 | CA1 (0.50) | RAB9ATLR2KDM4EPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5196422-A | Antiinflammatory agents, antiallergens | ICI PHARMA (FR) | 1993-03-23 | — | — | US | disclosed |
| US-5089513-A | Antiinflammatory agents; antiallergens; asthma; side effect reduction | ICI PHARMA (FR) | 1992-02-18 | — | — | US | disclosed |