Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17627325 | 0.79 | KDM4E (0.41) | ALDH1A1MAPTKDM4ETDP1RAB9A | |
| SCHEMBL90894 | 0.78 | ALDH1A1 (0.44) | ALDH1A1MAPTRAD51BCHEKMT2A | |
| SCHEMBL11479425 | 0.77 | ALDH1A1 (0.44) | ALDH1A1MAPTRAD51BCHEKMT2A | |
| SCHEMBL10506887 | 0.77 | SMN1; SMN2 (0.59) | MAPTKMT2AMEN1RAB9AHTT | |
| SCHEMBL823328 | 0.76 | LMNA (0.39) | KMT2AMEN1RAB9AGAAHTT | |
| SCHEMBL10852799 | 0.76 | HPGD (0.47) | ALDH1A1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL3758157 | 0.75 | ALDH1A1 (0.61) | ALDH1A1MAPTRAD51BCHEKMT2A | |
| SCHEMBL10504892 | 0.74 | GAA (0.40) | ALDH1A1MAPTKDM4EGFERTDP1 | |
| SCHEMBL11316710 | 0.74 | HSD17B10 (0.45) | ALDH1A1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL10660544 | 0.72 | POLB (0.53) | ALDH1A1MAPTRAD51BCHEKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0243450-B1 | PYRIDINYLUREA COMPOUNDS AND AGRICULTURAL USES | FMC Corporation (US) | 1993-04-28 | — | — | EP | disclosed |
| US-4808722-A | PLANT GROWTH REGULATORS | FMC CORPORATION (US) | 1989-02-28 | — | — | US | disclosed |