SCHEMBL9599518

SCHEMBL9599518

NC(=O)c1ccccc1Oc1ccnnn1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTNNB1 P35222 1/20 0.53
IRAK4 Q9NWZ3 1/20 0.44
MAPT P10636 3/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
NR1I2 O75469 1/20 0.42
LMNA P02545 1/20 0.42
CHRM2 P08172 1/20 0.42
CYP3A4 P08684 1/20 0.42
ADRA2A P08913 1/20 0.42
OPRK1 P41145 1/20 0.42
HTR2B P41595 1/20 0.42
SLC6A3 Q01959 1/20 0.42
HDAC6 Q9UBN7 1/20 0.42
TBXAS1 P24557 1/20 0.39
HTT P42858 2/20 0.39
KDM4E B2RXH2 2/20 0.39
PARP1 P09874 1/20 0.39
CSNK1A1 P48729 1/20 0.37
TYRO3 Q06418 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9601666 0.85 KMT2A (0.41) CTNNB1MAPTMEN1KMT2ALMNA
SCHEMBL9601655 0.79 ALDH1A1 (0.41) MAPTMEN1KMT2ALMNACYP3A4
SCHEMBL31414009 0.76 CTNNB1 (0.57) CTNNB1IRAK4MAPTMEN1KMT2A
SCHEMBL7428731 0.76 CTNNB1 (0.57) CTNNB1IRAK4MAPTMEN1KMT2A
SCHEMBL7693879 0.76 CTNNB1 (0.77) CTNNB1IRAK4MAPTMEN1KMT2A
SCHEMBL10908276 0.74 CTNNB1 (0.54) CTNNB1IRAK4MAPTMEN1KMT2A
SCHEMBL6267051 0.72 RAB9A (0.39) MAPTMEN1KMT2ALMNACYP3A4
SCHEMBL9592615 0.72 CTNNB1 (0.61) CTNNB1IRAK4MAPTMEN1KMT2A
SCHEMBL3421844 0.72 CTNNB1 (0.56) CTNNB1IRAK4MAPTMEN1KMT2A
SCHEMBL9692048 0.72 KDM4E (0.44) MAPTMEN1KMT2ALMNACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0493321-A1 Pyrimidinyl- and triazinyl-salicylamides, their use and their preparation CIBA-GEIGY AG (CH) 1992-07-01 EP claimed
JP-4321670-A None JP disclosed
US-5262386-A Herbicides and plant growth regulators, weed control and positive influence on crop plants CIBA-GEIGY CORPORATION (US) 1993-11-16 US disclosed
US-5262386-A Herbicides and plant growth regulators, weed control and positive influence on crop plants CIBA-GEIGY CORPORATION (US) 1993-11-16 US disclosed
US-5262386-A Herbicides and plant growth regulators, weed control and positive influence on crop plants CIBA-GEIGY CORPORATION (US) 1993-11-16 US disclosed
JP-H04321670-A PYRIMIDINYL-AND TRIAZINYLSALICYLAMIDES, METHOD FOR USING THEM AND THEIR PRODUCTION CIBA GEIGY AG 1992-11-11 JP disclosed
EP-0493321-A1 Pyrimidinyl- and triazinyl-salicylamides, their use and their preparation CIBA-GEIGY AG (CH) 1992-07-01 EP disclosed
EP-0493321-A1 Pyrimidinyl- and triazinyl-salicylamides, their use and their preparation CIBA-GEIGY AG (CH) 1992-07-01 EP disclosed
EP-0493321-A1 Pyrimidinyl- and triazinyl-salicylamides, their use and their preparation CIBA-GEIGY AG (CH) 1992-07-01 EP disclosed