Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 2/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8971172 | 0.88 | CCR3 (0.49) | CCR3ACHESLC6A3HTR2AHTR2C | |
| SCHEMBL8971180 | 0.88 | CCR3 (0.49) | CCR3ACHESLC6A3HTR2AHTR2C | |
| SCHEMBL8971088 | 0.81 | CCR3 (0.57) | CCR3ACHESLC6A3HTR2AHTR2C | |
| SCHEMBL8971084 | 0.81 | CCR3 (0.57) | CCR3ACHESLC6A3HTR2AHTR2C | |
| SCHEMBL9599973 | 0.78 | CCR3 (0.54) | CCR3ACHESLC6A3HTR1ASLC6A4 | |
| SCHEMBL8970113 | 0.76 | CCR3 (0.47) | CCR3ACHEHTR2A | |
| SCHEMBL8970124 | 0.76 | CCR3 (0.47) | CCR3ACHEHTR2A | |
| SCHEMBL8970108 | 0.76 | CCR3 (0.47) | CCR3ACHEHTR2A | |
| SCHEMBL8971056 | 0.75 | CCR3 (0.77) | CCR3ACHE | |
| SCHEMBL9427623 | 0.72 | CCR3 (0.56) | CCR3ACHEHTR2AHTR2CKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993022310-A1 | (N-PHTHALIMIDOALKYL)PIPERIDINES FOR THE TREATMENT OF PSYCHOSES | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1993-11-11 | — | — | WO | disclosed |